Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.71 |
| ▸ | CNR1 | P21554 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5015349 | 1.00 | CNR2 (0.71) | CNR2CNR1ALDH1A1MAPTKMT2A | |
| SCHEMBL15606927 | 0.89 | CNR2 (0.71) | CNR2CNR1ALDH1A1MAPTKMT2A | |
| SCHEMBL15526152 | 0.89 | CNR2 (0.71) | CNR2CNR1ALDH1A1MAPTKMT2A | |
| SCHEMBL22315788 | 0.85 | CNR2 (0.74) | CNR2CNR1ALDH1A1MAPTKMT2A | |
| SCHEMBL12555962 | 0.85 | ALDH1A1 (0.81) | CNR2CNR1ALDH1A1MAPTKMT2A | |
| SCHEMBL5016654 | 0.84 | MAPT (0.80) | CNR2CNR1ALDH1A1MAPTKMT2A | |
| SCHEMBL5016615 | 0.84 | MAPT (0.80) | CNR2CNR1ALDH1A1MAPTKMT2A | |
| SCHEMBL22315786 | 0.84 | CNR2 (0.73) | CNR2CNR1ALDH1A1MAPTKMT2A | |
| SCHEMBL20840229 | 0.84 | CNR2 (1.00) | CNR2CNR1ALDH1A1MAPTKMT2A | |
| SCHEMBL5015412 | 0.81 | CNR2 (0.50) | CNR2CNR1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012036383-A3 | USE OF A PROTEIN TYROSINE KINASE INHIBITOR FOR INDUCING THE DIFFERENTIATION OF MESENCHYMAL STEM CELLS INTO CARDIOGENIC CELLS | 파미셀 주식회사 (KR) | 2012-05-10 | — | — | WO | disclosed |
| EP-1927587-B1 | Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof | INT FLAVORS & FRAGRANCES INC (US) | 2011-12-07 | — | — | EP | disclosed |
| EP-1927587-A2 | Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof | INTERNATIONAL FLAVORS & FRAGRANCES, INC. (US) | 2008-06-04 | — | — | EP | disclosed |
| US-7329767-B2 | Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2008-02-12 | — | — | US | disclosed |
| US-7329767-B2 | Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2008-02-12 | — | — | US | disclosed |
| US-7329767-B2 | Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2008-02-12 | — | — | US | disclosed |
| US-20050075368-A1 | Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof | INTERNATIONAL FLAVORS & FRAGRANCES INC.WW | 2005-04-07 | — | — | US | disclosed |
| EP-1520850-A2 | Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2005-04-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075368-A1 | Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof | TAS2R41, TAS2R42, TAS2R14 | CNR2 1265/4885CNR1 1556/4885ALDH1A1 249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.