Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 4/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2090744 | 0.83 | GRIN1 (0.39) | SIGMAR1SMN1; SMN2DRD4MEN1 | |
| SCHEMBL2094328 | 0.80 | SMN1; SMN2 (0.41) | SMN1; SMN2 | |
| SCHEMBL27644609 | 0.70 | DRD2 (0.48) | SMN1; SMN2DRD2DRD3DRD4KDM4E | |
| SCHEMBL5542061 | 0.70 | SIGMAR1 (0.60) | SIGMAR1SMN1; SMN2DRD2DRD3DRD4 | |
| SCHEMBL1043952 | 0.70 | SIGMAR1 (0.85) | SIGMAR1SMN1; SMN2DRD2ALDH1A1LMNA | |
| SCHEMBL20804352 | 0.70 | SIGMAR1 (0.85) | SIGMAR1SMN1; SMN2DRD2ALDH1A1LMNA | |
| SCHEMBL19285228 | 0.70 | SIGMAR1 (0.85) | SIGMAR1SMN1; SMN2DRD2ALDH1A1LMNA | |
| SCHEMBL5013364 | 0.68 | TSHR (0.50) | DRD2DRD3DRD4ALDH1A1 | |
| SCHEMBL18234102 | 0.67 | SIGMAR1 (0.74) | RAB9ASIGMAR1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL5016241 | 0.67 | KDM4E (0.40) | SMN1; SMN2DRD2DRD3DRD4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |