Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LSS | P48449 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 7/20 | 0.41 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.39 |
| ▸ | PHGDH | O43175 | 1/20 | 0.39 |
| ▸ | GPR6 | P46095 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2088515 | 0.84 | NTRK1 (0.38) | NTRK1NTRK2DRD3 | |
| SCHEMBL27666102 | 0.80 | TSHR (0.50) | TSHRALDH1A1LSSDRD2TEAD1 | |
| SCHEMBL5015139 | 0.73 | PPARD (0.43) | TSHRALDH1A1LSSDRD2DRD4 | |
| SCHEMBL5013349 | 0.72 | KCNN4 (0.46) | TSHRALDH1A1DRD2DRD4GPR6 | |
| SCHEMBL5543182 | 0.70 | ALDH1A1 (0.62) | TSHRALDH1A1LSSDRD2DRD4 | |
| SCHEMBL8170370 | 0.69 | ALDH1A1 (0.58) | TSHRALDH1A1LSSDRD2DRD4 | |
| SCHEMBL5016235 | 0.68 | RAB9A (0.46) | ALDH1A1DRD2DRD4DRD3 | |
| SCHEMBL5016362 | 0.67 | CASP1 (0.38) | ALDH1A1DRD2DRD4DRD3 | |
| SCHEMBL2090465 | 0.67 | SCN4A (0.56) | TSHRALDH1A1SCN9APHGDHPPARD | |
| SCHEMBL2056209 | 0.67 | RAB9A (0.57) | TSHRALDH1A1SCN9APHGDHPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |