Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP4 | P49662 | 1/20 | 0.38 |
| ▸ | CASP5 | P51878 | 1/20 | 0.38 |
| ▸ | SRPK1 | Q96SB4 | 12/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5016368 | 0.88 | CASP1 (0.38) | CASP1CASP4CASP5SRPK1LMNA | |
| SCHEMBL2091003 | 0.84 | RPS6KB1 (0.38) | LMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL2093719 | 0.78 | LIPG (0.36) | — | |
| SCHEMBL5012794 | 0.78 | SCD (0.48) | LMNAKDM4EALDH1A1 | |
| SCHEMBL27644470 | 0.76 | DRD2 (0.43) | LMNASMN1; SMN2KDM4EALDH1A1DRD2 | |
| SCHEMBL2091008 | 0.72 | RPS6KB1 (0.38) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL5542057 | 0.71 | PPARD (0.50) | CASP1CASP4CASP5KDM4EALDH1A1 | |
| SCHEMBL5013426 | 0.71 | RBP4 (0.40) | LMNASMN1; SMN2KDM4EALDH1A1DRD2 | |
| SCHEMBL27665953 | 0.69 | KDM4E (0.52) | LMNASMN1; SMN2KDM4EALDH1A1DRD2 | |
| SCHEMBL5015139 | 0.69 | PPARD (0.43) | SMN1; SMN2KDM4EALDH1A1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |