SCHEMBL5017113

SCHEMBL5017113

NCCN1CCC[C@H]1C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.41
ACE P12821 7/20 0.41
CYP2C19 P33261 2/20 0.40
REN P00797 2/20 0.39
LMNA P02545 2/20 0.39
HSD17B10 Q99714 2/20 0.39
KDM4E B2RXH2 1/20 0.39
F2 P00734 1/20 0.39
LTA4H P09960 1/20 0.39
MAPT P10636 1/20 0.39
PEPD P12955 1/20 0.39
ALOX15 P16050 1/20 0.39
PTGS1 P23219 1/20 0.39
HTR2A P28223 1/20 0.39
PTGS2 P35354 1/20 0.39
HRH1 P35367 1/20 0.39
THPO P40225 1/20 0.39
PMP22 Q01453 1/20 0.39
ACE2 Q9BYF1 1/20 0.39
SLC6A1 P30531 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2674102 1.00 CYP1A2 (0.41) CYP1A2ACECYP2C19RENLMNA
SCHEMBL6516948 1.00 CYP1A2 (0.41) CYP1A2ACECYP2C19RENLMNA
SCHEMBL13545424 0.94 SMN1; SMN2 (0.43) CYP1A2ACECYP2C19LMNASLC6A1
SCHEMBL9090390 0.89 ACE (0.41) CYP1A2ACECYP2C19RENLMNA
SCHEMBL9090397 0.89 ACE (0.41) CYP1A2ACECYP2C19RENLMNA
SCHEMBL1645702 0.86 ACE (0.39) CYP1A2ACECYP2C19
SCHEMBL17052427 0.84 ACE (0.43) CYP1A2ACECYP2C19RENLMNA
SCHEMBL28452245 0.84 ACE (0.43) CYP1A2ACECYP2C19RENLMNA
SCHEMBL25030103 0.83 SLC6A9 (0.40) CYP1A2CYP2C19LTA4HSMN1; SMN2RAB9A
SCHEMBL25030104 0.83 SLC6A9 (0.40) CYP1A2CYP2C19LTA4HSMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260117001-A1 FLUOROPHORE-POLYMER CONJUGATES AND USES THEREOF ERISYON INC (US) 2026-04-30 US disclosed
WO-2024076928-A1 FLUOROPHORE-POLYMER CONJUGATES AND USES THEREOF ERISYON INC. (US) 2024-04-11 WO disclosed
EP-2291390-B1 NEW OPTICALLY PURE COMPOUNDS FOR IMPROVED THERAPEUTIC EFFICIENCY CENTRE NAT RECH SCIENT (FR) 2014-11-05 EP disclosed
EP-1513871-B1 PYRROLIDINYL PEPTIDE NUCLEIC ACIDS ISIS INNOVATION (GB) 2008-10-29 EP disclosed
US-7098321-B2 Homologous peptide nucleic acids ISIS INNOVATION LIMITED (GB) 2006-08-29 US disclosed
EP-1513871-A2 PYRROLIDINYL PEPTIDE NUCLEIC ACIDS Isis Innovation Limited (GB) 2005-03-16 EP disclosed
US-6716961-B2 Chiral peptide nucleic acids with a N-aminoethyl-d-proline backbone ISIS INNOVATION LIMITED (GB) 2004-04-06 US disclosed
US-6716961-B2 Chiral peptide nucleic acids with a N-aminoethyl-d-proline backbone ISIS INNOVATION LIMITED (GB) 2004-04-06 US disclosed
US-20030228588-A1 Homologous peptide nucleic acids ISIS INNOVATION LIMITED 2003-12-11 US disclosed
US-20030162699-A1 Chiral peptide nucleic acids with a n-aminoethyl-d-proline backbone ISIS INNOVATION LIMITED (GB) 2003-08-28 US disclosed
US-20030162699-A1 Chiral peptide nucleic acids with a n-aminoethyl-d-proline backbone ISIS INNOVATION LIMITED (GB) 2003-08-28 US disclosed
US-20030157500-A1 Pyrrolidinyl peptide nucleic acids ISIS INNOVATION LIMITED (GB) 2003-08-21 US disclosed
WO-2003066902-A2 PYRROLIDINYL PEPTIDE NUCLEIC ACIDS ISIS INNOVATION LIMITED (GB) 2003-08-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030157500-A1 Pyrrolidinyl peptide nucleic acids POLRMT, POLH, PCNA CYP1A2 4697/4885ACE 3500/4885CYP2C19 4031/4885
US-20030162699-A1 Chiral peptide nucleic acids with a n-aminoethyl-d-proline backbone POLL, HNRNPL, RNGTT CYP1A2 4864/4885ACE 391/4885CYP2C19 4676/4885
US-20030228588-A1 Homologous peptide nucleic acids HNRNPH3, PCNA, POLL CYP1A2 4709/4885ACE 3394/4885CYP2C19 4302/4885
US-20260117001-A1 FLUOROPHORE-POLYMER CONJUGATES AND USES THEREOF QPCTL, QRFPR, CD47 CYP1A2 4788/4885ACE 3469/4885CYP2C19 4339/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.