Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | DUT | P33316 | 10/20 | 0.55 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL592821 | 0.95 | L3MBTL1 (0.56) | L3MBTL1DUTPDE3ANAAA | |
| Uracil SCHEMBL7129487 | 0.88 | CRBN (0.49) | L3MBTL1DUTPDE3ACRBNNAAA | |
| SCHEMBL4348697 | 0.84 | L3MBTL1 (0.59) | L3MBTL1DUTCRBNPKM | |
| SCHEMBL5016827 | 0.81 | DUT (0.55) | L3MBTL1DUTPDE3ACRBNNAAA | |
| SCHEMBL3079985 | 0.81 | DUT (0.56) | L3MBTL1DUTCRBNNAAA | |
| SCHEMBL24263706 | 0.81 | DUT (0.55) | L3MBTL1DUTPDE3ACRBNNAAA | |
| SCHEMBL6864606 | 0.81 | DUT (0.57) | L3MBTL1DUTCRBNPKM | |
| SCHEMBL4957852 | 0.81 | DUT (0.55) | L3MBTL1DUTPDE3ACRBNNAAA | |
| SCHEMBL5016828 | 0.81 | DUT (0.55) | L3MBTL1DUTPDE3ACRBNNAAA | |
| SCHEMBL4372127 | 0.80 | PKM (0.51) | L3MBTL1DUTCRBNPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313751-B1 | NEW MACROLIDES WITH ANTIBACTERIAL ACTIVITY | BASILEA PHARMACEUTICA AG (CH) | 2008-09-17 | — | — | EP | disclosed |
| US-6740642-B2 | ACTIVE AGAINST GRAM POSITIVE PATHOGENS SUCH AS STAPHYLOCOCCUS AUREUS, STREPTOCOCCUS PNEUMONIAE, GRAM NEGATIVE STRAINS SUCH AS HAEMOPHILUS INFLUENZAE; IMPROVED STABILITY | BASILEA PARMACEUTICA AG (CH) | 2004-05-25 | — | — | US | disclosed |