Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.58 |
| ▸ | DUT | P33316 | 10/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14861415 | 0.89 | L3MBTL1 (0.54) | L3MBTL1CRBNDUTPKMALDH1A1 | |
| SCHEMBL4286089 | 0.87 | PKM (0.57) | L3MBTL1CRBNDUTPKM | |
| SCHEMBL2990980 | 0.87 | L3MBTL1 (0.53) | L3MBTL1CRBNDUTPKMALDH1A1 | |
| SCHEMBL3235869 | 0.87 | L3MBTL1 (0.53) | L3MBTL1CRBNDUTPKMALDH1A1 | |
| SCHEMBL5024016 | 0.87 | L3MBTL1 (0.53) | L3MBTL1CRBNDUTPKMALDH1A1 | |
| SCHEMBL2983407 | 0.87 | ALDH1A1 (0.57) | L3MBTL1CRBNDUTPKMALDH1A1 | |
| SCHEMBL5024015 | 0.87 | L3MBTL1 (0.53) | L3MBTL1CRBNDUTPKMALDH1A1 | |
| SCHEMBL16632410 | 0.87 | L3MBTL1 (0.53) | L3MBTL1CRBNDUTPKMALDH1A1 | |
| SCHEMBL10924758 | 0.86 | PKM (0.55) | L3MBTL1CRBNDUTPKMALDH1A1 | |
| SCHEMBL24263706 | 0.84 | DUT (0.55) | L3MBTL1CRBNDUTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2124919-A2 | METHODS FOR MODULATING BONE FORMATION AND MINERALIZATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2009-12-02 | — | — | EP | claimed |
| WO-2008103314-A2 | METHODS FOR MODULATING BONE FORMATION AND MINERALIZATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2008-08-28 | — | — | WO | claimed |
| EP-2124919-A2 | METHODS FOR MODULATING BONE FORMATION AND MINERALIZATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008103314-A2 | METHODS FOR MODULATING BONE FORMATION AND MINERALIZATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2008-08-28 | — | — | WO | disclosed |