Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | EHMT2 | Q96KQ7 | 9/20 | 0.48 |
| ▸ | EHMT1 | Q9H9B1 | 6/20 | 0.48 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.47 |
| ▸ | SPIN1 | Q9Y657 | 2/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.46 |
| ▸ | SRC | P12931 | 2/20 | 0.46 |
| ▸ | FLT4 | P35916 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | TEK | Q02763 | 2/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.46 |
| ▸ | PLK4 | O00444 | 1/20 | 0.46 |
| ▸ | GAK | O14976 | 1/20 | 0.46 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.46 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | STK10 | O94804 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4373064 | 0.84 | FLT4 (0.62) | FGFR2PDGFRBSRCFLT4KDR | |
| SCHEMBL4374150 | 0.83 | ABCB11 (0.63) | FGFR2PDGFRBSRCFLT4KDR | |
| SCHEMBL4377420 | 0.79 | FLT4 (0.57) | LTA4HFGFR2PDGFRBSRCFLT4 | |
| SCHEMBL4380889 | 0.79 | ABCB11 (0.57) | LTA4HFGFR2PDGFRBSRCFLT4 | |
| SCHEMBL4380404 | 0.78 | FLT4 (0.63) | FGFR2PDGFRBSRCFLT4KDR | |
| SCHEMBL4375714 | 0.78 | KDR (0.62) | FGFR2PDGFRBSRCFLT4KDR | |
| SCHEMBL4381975 | 0.78 | ABCB11 (0.62) | FGFR2PDGFRBSRCFLT4KDR | |
| SCHEMBL5015542 | 0.77 | KDR (0.74) | EHMT2EHMT1FGFR2PDGFRBSRC | |
| SCHEMBL4379769 | 0.77 | SRC (0.60) | FGFR2PDGFRBSRCFLT4KDR | |
| SCHEMBL13627281 | 0.77 | LTA4H (0.52) | LTA4HEHMT2EHMT1FGFR2SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309587-B1 | CINNOLINE COMPOUNDS | ASTRAZENECA AB (SE) | 2008-12-31 | — | — | EP | disclosed |
| US-6887874-B2 | Cinnoline compounds | ASTRAZENECA AB (SE) | 2005-05-03 | — | — | US | disclosed |
| US-20030212055-A1 | Cinnoline compounds | ASTRAZENECA AB (SE) | 2003-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212055-A1 | Cinnoline compounds | VEGFA, PGF, CCR7 | LTA4H 2989/4885EHMT2 3136/4885EHMT1 2064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.