Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | GABRP | O00591 | 4/20 | 0.49 |
| ▸ | GABRD | O14764 | 4/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.49 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.49 |
| ▸ | GABRE | P78334 | 4/20 | 0.49 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.49 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.49 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.49 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28589144 | 0.87 | PARP14 (0.52) | KIF11KDM4EGABRPGABRDGABRA1 | |
| SCHEMBL27955668 | 0.87 | KDM4E (0.54) | KIF11KDM4EGABRPGABRDGABRA1 | |
| SCHEMBL898343 | 0.84 | KDM4E (0.50) | KIF11KDM4EGABRPGABRDGABRA1 | |
| SCHEMBL28194700 | 0.83 | KDM4E (0.49) | KIF11KDM4EGABRPGABRDGABRA1 | |
| SCHEMBL28398234 | 0.82 | KDM4E (0.48) | KIF11KDM4EGABRPGABRDGABRA1 | |
| SCHEMBL5746662 | 0.81 | HTR1B (0.51) | KIF11KDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL5745718 | 0.81 | HTR1B (0.61) | KIF11KDM4EMAPTMAPK1KMT2A | |
| SCHEMBL29446056 | 0.80 | KDM4E (0.58) | KIF11KDM4EGABRPGABRDGABRA1 | |
| SCHEMBL896249 | 0.80 | KDM4E (0.58) | KIF11KDM4EGABRPGABRDGABRA1 | |
| SCHEMBL29366918 | 0.80 | KIF11 (0.46) | KIF11KDM4EGABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110452899-A | A kind of glucose isomerase, mutant and its preparing the application in D-Fructose | UNIV ZHEJIANG TECHNOLOGY | 2019-11-15 | — | — | CN | disclosed |
| CN-106399396-B | A method of knocking out wecA reduces Klebsiella capsular polysaccharide content | 江南大学 | 2019-10-18 | — | — | CN | disclosed |
| CN-109415716-A | Arabinose isomerase for yeast | 纳幕尔杜邦公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-108690723-A | A kind of preparation method of the happy fragrance of fragrant plant | 熊哲闻 | 2018-10-23 | — | — | CN | disclosed |
| CN-104962394-B | A kind of method that mucor processing pineapple juice prepares cigarette pineapple flavors | 湖北中烟工业有限责任公司 | 2018-08-31 | — | — | CN | disclosed |
| US-10043978-B2 | Organic semiconductor formulations | FLEXTERRA, INC. (US) | 2018-08-07 | — | — | US | disclosed |
| CN-106366260-B | A kind of yellow light copolymer hybrid material and preparation method thereof | 福建师范大学 | 2018-07-17 | — | — | CN | disclosed |
| CN-106366260-A | Yellow-light copolymer hybrid material and preparation method thereof | 福建师范大学 | 2017-02-01 | — | — | CN | disclosed |
| CN-106349425-A | Preparation method of organic and inorganic hybridized polymer fluorescent powder and application of organic and inorganic hybridized polymer fluorescent powder to LED (Light Emitting Diode) | 福建师范大学 | 2017-01-25 | — | — | CN | disclosed |
| US-20170012208-A1 | ORGANIC SEMICONDUCTOR FORMULATIONS | USINVEST LLC | 2017-01-12 | — | — | US | disclosed |
| CN-101613321-A | The list and the bicyclic pyrrole derivatives that suppress part and advanced glycation end product acceptor interaction | TRANSTECH PHARMA INC | 2009-12-30 | — | — | CN | disclosed |
| CN-101597262-A | The list and the bicyclic pyrrole derivatives that suppress part and advanced glycation end product acceptor interaction | TRANSTECH PHARMA INC (US) | 2009-12-09 | — | — | CN | disclosed |
| CN-100525763-C | Mono-and bicyclic pyrrole derivatives inhibiting ligand interaction with higher glycation end product receptors | TRANSTECH PHARMA INC (US) | 2009-08-12 | — | — | CN | disclosed |
| US-20080146810-A1 | NOVEL TRICYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS S.A. (CH) | 2008-06-19 | — | — | US | disclosed |
| EP-1554262-B1 | NOVEL TRICYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LTD (IN) | 2007-12-05 | — | — | EP | disclosed |
| US-7238725-B2 | Tricyclic compounds useful for the treatment of inflammatory and allergic disorders: process for their preparation and pharmaceutical compositions containing them | GLENMARK PHARMACEUTICALS LTD. (IN) | 2007-07-03 | — | — | US | disclosed |
| US-20060178418-A1 | Novel tricyclic compounds useful for the treatment of inflammatory and allergic disorders:process for their preparation and pharmaceutical compositions containing them | GLENMARK PHARMACEUTICALS LTD. (IN) | 2006-08-10 | — | — | US | disclosed |
| EP-1554262-A1 | NOVEL TRICYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Glenmark Pharmaceuticals Limited (IN) | 2005-07-20 | — | — | EP | disclosed |
| CN-1633290-A | Mono-and bicyclic pyrrole derivatives inhibiting ligand interaction with higher glycation end product receptors | TRANSTECH PHARMA INC (US) | 2005-06-29 | — | — | CN | disclosed |
| WO-2004037805-A1 | NOVEL TRICYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LTD. (US) | 2004-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146810-A1 | NOVEL TRICYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LTC4S, TSLP, GPR119 | KIF11 4711/4885KDM4E 4205/4885GABRP 922/4885 |
| US-20060178418-A1 | Novel tricyclic compounds useful for the treatment of inflammatory and allergic disorders:process for their preparation and pharmaceutical compositions containing them | LTC4S, TSLP, GPR119 | KIF11 4711/4885KDM4E 4205/4885GABRP 922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.