Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA6 | P23280 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | TPMT | P51580 | 6/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14417485 | 0.91 | ELANE (0.41) | ELANECA12CA1CA2CA4 | |
| SCHEMBL21824325 | 0.81 | TPMT (0.50) | ELANECA12CA1CA2CA4 | |
| SCHEMBL27051801 | 0.79 | ELANE (0.49) | ELANECA12CA1CA2CA4 | |
| SCHEMBL2221010 | 0.77 | ELANE (0.49) | ELANECA12CA1CA2CA7 | |
| SCHEMBL2223556 | 0.74 | ELANE (0.52) | ELANECA2 | |
| SCHEMBL27051629 | 0.74 | TSHR (0.49) | ELANECA12CA1CA2CA4 | |
| SCHEMBL4046263 | 0.73 | CASP6 (0.53) | ELANETSHRALDH1A1MAPT | |
| SCHEMBL31597010 | 0.73 | ELANE (0.43) | ELANECA12CA1CA2CA4 | |
| SCHEMBL19859253 | 0.73 | ELANE (0.43) | ELANECA12CA1CA2CA4 | |
| SCHEMBL16785677 | 0.72 | ACHE (0.48) | ELANEPKMKDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651200-B1 | GALLOYLPEPTIDES | ASTELLAS PHARMA INC (JP) | 2008-12-24 | — | — | EP | claimed |
| US-7273951-B2 | Polyhydroxy phenols and their use in binding p-selectin | ASTELLAS PHARMA INC. (JP) | 2007-09-25 | — | — | US | claimed |
| US-20060276545-A1 | Polyhydroxy phenols and their use in binding p-selectin | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 2006-12-07 | — | — | US | claimed |
| EP-1651200-A1 | POLYHYDROXY PHENOLS AND THEIR USE IN BINDNG P-SELECTIN | Astellas Pharma Inc. (JP) | 2006-05-03 | — | — | EP | claimed |
| WO-2004105740-A1 | POLYHYDROXY PHENOLS AND THEIR USE IN BINDNG P-SELECTIN | ASTELLAS PHARMA INC. (JP) | 2004-12-09 | — | — | WO | claimed |
| EP-1651200-B1 | GALLOYLPEPTIDES | ASTELLAS PHARMA INC (JP) | 2008-12-24 | — | — | EP | disclosed |
| US-7273951-B2 | Polyhydroxy phenols and their use in binding p-selectin | ASTELLAS PHARMA INC. (JP) | 2007-09-25 | — | — | US | disclosed |
| US-7273951-B2 | Polyhydroxy phenols and their use in binding p-selectin | ASTELLAS PHARMA INC. (JP) | 2007-09-25 | — | — | US | disclosed |
| US-20060276545-A1 | Polyhydroxy phenols and their use in binding p-selectin | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1651200-A1 | POLYHYDROXY PHENOLS AND THEIR USE IN BINDNG P-SELECTIN | Astellas Pharma Inc. (JP) | 2006-05-03 | — | — | EP | disclosed |
| WO-2004105740-A1 | POLYHYDROXY PHENOLS AND THEIR USE IN BINDNG P-SELECTIN | ASTELLAS PHARMA INC. (JP) | 2004-12-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276545-A1 | Polyhydroxy phenols and their use in binding p-selectin | SELP, SELPLG, SELE | ELANE 162/4885CA12 2669/4885CA1 3907/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.