Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CASP1 | P29466 | 12/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19511367 | 0.89 | ALDH1A1 (0.53) | ALDH1A1CASP1TACR1MAPK1L3MBTL1 | |
| SCHEMBL7753516 | 0.89 | ALDH1A1 (0.53) | ALDH1A1CASP1TACR1MAPK1L3MBTL1 | |
| SCHEMBL31276678 | 0.88 | ABCB1 (0.51) | ALDH1A1CASP1TACR1LMNAMAPK1 | |
| SCHEMBL29443514 | 0.86 | CASP1 (0.48) | ALDH1A1CASP1HTTLMNASMN1; SMN2 | |
| SCHEMBL8351818 | 0.85 | ALDH1A1 (0.53) | ALDH1A1TACR1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL21444696 | 0.85 | ALDH1A1 (0.53) | ALDH1A1TACR1MAPK1L3MBTL1 | |
| SCHEMBL13108402 | 0.85 | TACR1 (0.58) | ALDH1A1TACR1 | |
| SCHEMBL2059140 | 0.85 | TACR1 (0.58) | ALDH1A1TACR1 | |
| SCHEMBL8348342 | 0.85 | ALDH1A1 (0.53) | ALDH1A1TACR1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL28750936 | 0.84 | TACR1 (0.61) | ALDH1A1CASP1TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085756-A1 | MACROCYCLIC COMPOUNDS AND METHODS OF TREATMENT | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2025-04-24 | — | — | WO | disclosed |
| US-10745692-B2 | Production method for charged non-protein amino acid-containing peptide | THE UNIVERSITY OF TOKYO (JP) | 2020-08-18 | — | — | US | disclosed |
| US-20160289668-A1 | Production Method for Charged Non-Protein Amino Acid-Containing Peptide | THE UNIVERSITY OF TOKYO (JP) | 2016-10-06 | — | — | US | disclosed |
| EP-3031915-A1 | PRODUCTION METHOD FOR CHARGED NON-PROTEIN AMINO ACID-CONTAINING PEPTIDE | The University of Tokyo (JP) | 2016-06-15 | — | — | EP | disclosed |
| WO-2015019999-A1 | PRODUCTION METHOD FOR CHARGED NON-PROTEIN AMINO ACID-CONTAINING PEPTIDE | 国立大学法人東京大学 (JP) | 2015-02-12 | — | — | WO | disclosed |
| US-8178490-B2 | Polybasic bacterial efflux pump inhibitors and therapeutic uses thereof | REMPEX PHARMACEUTICALS, INC. (US) | 2012-05-15 | — | — | US | disclosed |
| US-20100152098-A1 | POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | MPEX PHARMACEUTICALS, INC. (US) | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152098-A1 | POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | ABCB11, ABCB1, SLC47A1 | ALDH1A1 4062/4885CASP1 3606/4885HTT 3780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.