SCHEMBL501960

SCHEMBL501960

Cc1ccc([N+](=O)[O-])cc1C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.63
MAPT P10636 4/20 0.63
TDP1 Q9NUW8 4/20 0.60
TSHR P16473 3/20 0.60
CYP3A4 P08684 3/20 0.59
ALOX15 P16050 1/20 0.59
HTT P42858 2/20 0.58
TP53 P04637 1/20 0.58
CTSV O60911 2/20 0.54
CTSL P07711 2/20 0.54
KMT2A Q03164 4/20 0.54
MEN1 O00255 3/20 0.54
SMN1; SMN2 Q16637 1/20 0.53
POLB P06746 1/20 0.50
PKM P14618 1/20 0.50
NPY1R P25929 1/20 0.50
NPY2R P49146 1/20 0.50
GAA P10253 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL8034446 0.98 ALDH1A1 (0.61) ALDH1A1MAPTTDP1TSHRCYP3A4
SCHEMBL6554357 0.85 ALDH1A1 (0.60) ALDH1A1MAPTTDP1TSHRCYP3A4
SCHEMBL31415352 0.85 ALDH1A1 (0.60) ALDH1A1MAPTTDP1TSHRCYP3A4
SCHEMBL33664 0.85 ALDH1A1 (0.64) ALDH1A1MAPTTDP1TSHRCYP3A4
SCHEMBL2371651 0.85 ALDH1A1 (0.64) ALDH1A1MAPTTDP1TSHRCYP3A4
SCHEMBL31557908 0.85 ALDH1A1 (0.56) ALDH1A1MAPTTDP1TSHRCYP3A4
SCHEMBL510143 0.84 ALDH1A1 (0.58) ALDH1A1MAPTTDP1TSHRCYP3A4
SCHEMBL4437870 0.84 KMT2A (0.60) ALDH1A1MAPTTDP1TSHRCYP3A4
Hydrochloric Acid SCHEMBL3133108 0.84 ALDH1A1 (0.62) ALDH1A1MAPTTDP1TSHRCYP3A4
SCHEMBL13844164 0.84 KMT2A (0.60) ALDH1A1MAPTTDP1TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 860 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119409619-A Isoindolone derivative and preparation method thereof 辽宁石油化工大学 2025-02-11 CN claimed
CN-119080334-A Comprehensive utilization method of nitric acid containing organic matters 山东友道化学有限公司 2024-12-06 CN claimed
US-9932473-B2 Encapsulating resin composition, semiconductor device using the encapsulating resin composition, and method for manufacturing semiconductor device using the encapsulating resin composition PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2018-04-03 US claimed
EP-0927714-B1 PROCESS FOR THE SEPARATION OF NITROTOLUIC ACID ISOMERS SUMIKIN CHEMICAL (JP) 2002-04-10 EP claimed
US-6054609-A ADDING AN AROMATIC ORGANIC BASE TO MIXTURE OF 3-NITRO-O-TOLUIC ACID AND 5-NITRO-O-TOLUIC ACID AND EFFICIENTLY RECOVERING BOTH 3-NITRO-O-TOLUIC ACID AND 5-NITRO-O-TOLUIC ACID BY TAKING ADVANTAGE OF DIFFERENCE BETWEEN IN THEIR SOLUBILITY TO WATER SUMIKIN CHEMICAL CO., LTD. (JP) 2000-04-25 US claimed
EP-0927714-A1 PROCESS FOR THE SEPARATION OF NITROTOLUIC ACID ISOMERS SUMIKIN CHEMICAL CO., LTD. (JP) 1999-07-07 EP claimed
EP-0902683-A1 AGONISTS IN THE COSTIMULATION OF TcR/CD3-INDUCED T-LYMPHOCYTES RADOPATH LIMITED (GB) 1999-03-24 EP claimed
WO-1997034593-A1 AGONISTS IN THE COSTIMULATION OF TcR/CD3-INDUCED T-LYMPHOCYTES RADOPATH LIMITED (GB) 1997-09-25 WO claimed
JP-10324667-A None JP disclosed
WO-2026098644-A1 TARGETED PROTEIN DEGRADATION AGENT, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF 北京森妙生物科技有限公司 2026-05-15 WO disclosed
US-12590066-B2 Fused-heterocyclyl-carbonohydrazonoyl dicyanide compounds and use thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2026-03-31 US disclosed
CN-121270371-A Preparation method of 3-chloro-5-fluoro-2-methylbenzoic acid 潍坊市海欣药业有限公司 2026-01-06 CN disclosed
US-20250289826-A1 PLPRO PROTEIN INHIBITOR, AND PREPARATION METHOD AND APPLICATION THEREOF TSINGHUA UNIVERSITY (CN) 2025-09-18 US disclosed
US-12391663-B2 Isoindolinone compounds MONTE ROSA THERAPEUTICS AG (CH) 2025-08-19 US disclosed
US-4192947-A REACTING DIAMINO NITROBENZENE WITH NITROBENZOYL CHLORIDE, CYCLIZING ANILIDE IN AQUEOUS ALKALI, REDUCING NITRO GROUPS WITH SULFIDE CASSELLA AKTIENGESELLSCHAFT (DE) 1980-03-11 US disclosed
EP-0001246-A1 Preparation of 2-(3'- or 4'-aminophenyl)-5(or 6)-aminobenzimidazoles CASSELLA Aktiengesellschaft (DE) 1979-04-04 EP disclosed
US-4127602-A Methyl substituted hydroxynaphthalenesulfonic acid ureides and salts as complement inhibitors AMERICAN CYANAMID COMPANY (US) 1978-11-28 US disclosed
US-4103028-A SUBSTITUTED HYDROXY NAPHTHALENEDISULFONIC ACIDS AMERICAN CYANAMID COMPANY (US) 1978-07-25 US disclosed
US-4046805-A Substituted-hydroxy-naphthalenedisulfonic acid compounds AMERICAN CYANAMID COMPANY (US) 1977-09-06 US disclosed
US-4036838-A Process for the production of nitro derivatives of aromatic compounds BAYER AKTIENGESELLSCHAFT (DT) 1977-07-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12391663-B2 Isoindolinone compounds CYP4F2, AOC2, AOC3 ALDH1A1 1142/4885MAPT 4795/4885TDP1 4627/4885
US-12590066-B2 Fused-heterocyclyl-carbonohydrazonoyl dicyanide compounds and use thereof H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CBR1, CLIC1 ALDH1A1 592/4885MAPT 4672/4885TDP1 2103/4885
US-20250289826-A1 PLPRO PROTEIN INHIBITOR, AND PREPARATION METHOD AND APPLICATION THEREOF ACE, PLP2, ACE2 ALDH1A1 3835/4885MAPT 676/4885TDP1 2645/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.