Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.45 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.43 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11318126 | 0.88 | CTSL (0.51) | KMT2ALMNAMEN1ALDH1A1HTT | |
| SCHEMBL5020122 | 0.83 | KMT2A (0.45) | KMT2ALMNAMEN1ALDH1A1HTT | |
| SCHEMBL3700040 | 0.83 | KMT2A (0.45) | KMT2ALMNAMEN1ALDH1A1HTT | |
| SCHEMBL9465072 | 0.83 | POLB (0.57) | KMT2ALMNAMEN1ALDH1A1HTT | |
| SCHEMBL9465077 | 0.83 | POLB (0.57) | KMT2ALMNAMEN1ALDH1A1HTT | |
| SCHEMBL7615422 | 0.81 | HDAC3 (0.44) | KMT2ALMNAMEN1ALDH1A1HTT | |
| SCHEMBL12308201 | 0.80 | CYP26A1 (0.49) | KMT2AMEN1ALDH1A1HTTNPSR1 | |
| SCHEMBL12574370 | 0.78 | TAS1R3 (0.47) | KMT2AALDH1A1HTTCYP26A1SMN1; SMN2 | |
| SCHEMBL12308256 | 0.76 | CYP26A1 (0.55) | CYP26A1RAB9A | |
| SCHEMBL9338561 | 0.76 | NPC1 (0.53) | KMT2ALMNAMEN1ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012065102-A2 | S-T-BUTYL PROTECTED CYSTEINE DI-PEPTIDE ANALOGS AND RELATED COMPOUNDS | PROMENTIS PHARMACEUTICALS, INC. (US) | 2012-05-18 | — | — | WO | disclosed |