Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TACR1 | P25103 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3697165 | 0.87 | TACR1 (0.44) | POLBTACR1GAARAB9AKMT2A | |
| SCHEMBL5020063 | 0.87 | TACR1 (0.44) | POLBTACR1GAARAB9AKMT2A | |
| SCHEMBL13296315 | 0.86 | TACR1 (0.64) | POLBTACR1KMT2AACEMBTPS1 | |
| SCHEMBL13050803 | 0.86 | GAA (0.50) | POLBTACR1GAARAB9AKMT2A | |
| SCHEMBL11940464 | 0.86 | CASP1 (0.52) | POLBTACR1GAARAB9AKMT2A | |
| SCHEMBL7612584 | 0.85 | HDAC3 (0.51) | POLBTACR1GAARAB9AKMT2A | |
| SCHEMBL25491959 | 0.83 | MMP9 (0.51) | POLBTACR1GAARAB9AKMT2A | |
| SCHEMBL14601755 | 0.82 | ALDH1A1 (0.50) | POLBTACR1RAB9AKMT2AMME | |
| SCHEMBL25492010 | 0.82 | ABCB1 (0.47) | POLBTACR1GAARAB9AKMT2A | |
| SCHEMBL11940461 | 0.82 | POLB (0.51) | POLBTACR1GAARAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012065102-A2 | S-T-BUTYL PROTECTED CYSTEINE DI-PEPTIDE ANALOGS AND RELATED COMPOUNDS | PROMENTIS PHARMACEUTICALS, INC. (US) | 2012-05-18 | — | — | WO | disclosed |