Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.48 |
| ▸ | KCNQ3 | O43525 | 4/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 4/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.38 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.38 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | BCL9 | O00512 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5020144 | 0.88 | PRMT1 (0.44) | KCNQ3KCNQ2MAPTALDH1A1MEN1 | |
| SCHEMBL3078521 | 0.77 | USP30 (0.49) | USP30KCNQ3KCNQ2HTR2BMAPT | |
| SCHEMBL3083418 | 0.75 | KCNQ3 (0.44) | USP30KCNQ3KCNQ2HTR2BMAPT | |
| SCHEMBL14615719 | 0.72 | GPR55 (0.59) | USP30KCNQ3KCNQ2HTR2BMAPT | |
| SCHEMBL3088538 | 0.70 | MMP2 (0.67) | — | |
| SCHEMBL5020143 | 0.69 | MMP8 (0.39) | — | |
| SCHEMBL14012554 | 0.69 | MMP2 (0.60) | HTR2BLMNA | |
| SCHEMBL12855775 | 0.69 | MMP2 (0.60) | HTR2BLMNA | |
| SCHEMBL5020184 | 0.68 | BRD4 (0.43) | MEN1KMT2A | |
| SCHEMBL23352871 | 0.65 | TRPV1 (0.68) | KCNQ3KCNQ2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064943-A2 | METALLOENZYME INHIBITOR COMPOUNDS | VIAMET PHARMACEUTICALS, INC. (US) | 2012-05-18 | — | — | WO | disclosed |