Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
| ▸ | PCTP | Q9UKL6 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.39 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5020190 | 0.88 | USP30 (0.48) | MEN1KMT2AMAPTALDH1A1KCNQ3 | |
| SCHEMBL3093412 | 0.77 | PRMT1 (0.52) | PRMT1PCTPCA1CA2MEN1 | |
| SCHEMBL3079053 | 0.75 | PRMT1 (0.46) | PRMT1PCTPCA1CA2MEN1 | |
| SCHEMBL5020143 | 0.69 | MMP8 (0.39) | — | |
| SCHEMBL12190100 | 0.66 | MEN1 (0.71) | MEN1KMT2AMAPTKDM4ENPC1 | |
| SCHEMBL3096015 | 0.65 | ADAMTS4 (0.58) | PRMT1CA1CA2MEN1KMT2A | |
| SCHEMBL30926464 | 0.65 | GRM4 (0.68) | PRMT1PCTPMEN1KMT2AMAPT | |
| SCHEMBL27181171 | 0.65 | GRM4 (0.68) | PRMT1PCTPMEN1KMT2AMAPT | |
| SCHEMBL4254970 | 0.63 | RAB9A (0.75) | MEN1KMT2AMAPTKDM4ENPC1 | |
| SCHEMBL9467786 | 0.63 | FLT1 (0.67) | PRMT1PCTPCA1CA2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064943-A2 | METALLOENZYME INHIBITOR COMPOUNDS | VIAMET PHARMACEUTICALS, INC. (US) | 2012-05-18 | — | — | WO | disclosed |