Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EYA3 | Q99504 | 5/20 | 0.77 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.77 |
| ▸ | SLC22A12 | Q96S37 | 6/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | TTR | P02766 | 1/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14552011 | 0.91 | EYA3 (0.72) | EYA3PTPN1SLC22A12CYP2C9TTR | |
| SCHEMBL5226741 | 0.91 | EYA3 (0.72) | EYA3PTPN1SLC22A12CYP2C9TTR | |
| SCHEMBL5020569 | 0.91 | SLC22A12 (0.68) | EYA3PTPN1SLC22A12CYP2C9NR1H4 | |
| SCHEMBL4567255 | 0.90 | EYA3 (0.70) | EYA3PTPN1SLC22A12CYP2C9TTR | |
| SCHEMBL11817673 | 0.90 | EYA3 (0.70) | EYA3PTPN1SLC22A12CYP2C9TTR | |
| SCHEMBL5224414 | 0.89 | EYA3 (0.69) | EYA3PTPN1SLC22A12CYP2C9TTR | |
| SCHEMBL5671722 | 0.88 | EYA3 (0.67) | EYA3PTPN1SLC22A12CYP2C9TTR | |
| SCHEMBL28162857 | 0.88 | EYA3 (0.67) | EYA3PTPN1SLC22A12CYP2C9TTR | |
| SCHEMBL6140040 | 0.88 | EYA3 (0.67) | EYA3PTPN1SLC22A12CYP2C9TTR | |
| SCHEMBL5227159 | 0.87 | EYA3 (0.66) | EYA3PTPN1SLC22A12CYP2C9TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012062918-A1 | PROCESS FOR THE PREPARATION OF 3-AROYL-5-AMINOBENZOFURAN DERIVATIVES | LEK PHARMACEUTICALS D.D. (SI) | 2012-05-18 | — | — | WO | disclosed |