Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | CPT2 | P23786 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7917810 | 1.00 | HMGCR (0.46) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL5004245 | 1.00 | HMGCR (0.46) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL11134540 | 0.80 | ALDH1A1 (0.30) | TDP1ALDH1A1 | |
| SCHEMBL11449359 | 0.80 | ALDH1A1 (0.30) | TDP1ALDH1A1 | |
| SCHEMBL11134527 | 0.80 | ALDH1A1 (0.30) | TDP1ALDH1A1 | |
| SCHEMBL27324574 | 0.80 | HMGCR (0.46) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL22070965 | 0.78 | HMGCR (0.44) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL10880649 | 0.78 | HMGCR (0.44) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL28702595 | 0.78 | HMGCR (0.44) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 | |
| SCHEMBL10880652 | 0.78 | HMGCR (0.44) | HMGCRCHRM1TBXA2RADRA1ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391580-A | Polymer layer directly attached to polypropylene tube and active heparin linked through covalent bond to the layer | ANATRACE INC. (US) | 1995-02-21 | — | — | US | claimed |
| CN-102001940-B | Continuous synthesis method for methyl 3,3-dimethyl pentenoate | JIANGSU YOUTH CHEMICAL CO LTD | 2013-07-24 | — | — | CN | disclosed |
| US-8318767-B2 | Substituted imidazoles as bombesin receptor subtype-3 modulators | MERCK SHARP & DOHME CORP (US) | 2012-11-27 | — | — | US | disclosed |
| US-8193228-B2 | Substituted imidazole as bombesin receptor subtype-3 modulators | MERCK SHARP & DOHME CORP. (US) | 2012-06-05 | — | — | US | disclosed |
| US-20120088788-A1 | SUBSTITUTED IMIDAZOLES AS BOMBESIN RECEPTOR SUBTYPE-3 MODULATORS | SCHERING CORPORATION | 2012-04-12 | — | — | US | disclosed |
| US-8106070-B2 | Substituted imidazoles as bombesin receptor subtype-3 modulators | MERCK SHARP & DOHME CORP. (US) | 2012-01-31 | — | — | US | disclosed |
| CN-102001940-A | Continuous synthesis method for methyl-3,3-dimethyl-4-pentenoate | YOUTH CHEMICAL CO LTD | 2011-04-06 | — | — | CN | disclosed |
| CN-102001940-A | Continuous synthesis method for methyl-3,3-dimethyl-4-pentenoate | YOUTH CHEMICAL CO LTD | 2011-04-06 | — | — | CN | disclosed |
| US-20100022598-A1 | Substituted inmidazoles as bombesin receptor subtype-3 modulators | MERCK SHARP & DOHME LLC | 2010-01-28 | — | — | US | disclosed |
| US-20100004280-A1 | Substituted imidazoles as bombesin receptor subtype-3 modulators | ALBANY MOLECULAR RESEARCH, INC. | 2010-01-07 | — | — | US | disclosed |
| EP-0998504-A1 | POLYMERIZATION OF OLEFINS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-05-10 | — | — | EP | disclosed |
| US-6046281-A | REACTING A LIVING CATIONIC POLYMER WITH AN ORGANIC COMPOUND HAVING AT LEAST 2 FURAN RINGS IN ITS MOLECULE, SUCH AS DIFURANYLHEXANE IN THE PRESENCE OF A LEWIS ACID | UNIVERSITY OF MASSACHUSETTS LOWELL (US) | 2000-04-04 | — | — | US | disclosed |
| WO-1999054324-A1 | PREPARATION OF CIS-6,6-DIMETHYL-3-OXA-BICYCLO[3.1.0]HEXAN-2-ONE | ZENECA LIMITED (GB) | 1999-10-28 | — | — | WO | disclosed |
| WO-1999024480-A1 | METHOD FOR COUPLING LIVING CATIONIC POLYMERS | DOW CORNING CORPORATION (US) | 1999-05-20 | — | — | WO | disclosed |
| WO-1999006397-A2 | PYRROLIDINE-3-CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGONISTS | ABBOTT LABORATORIES (US) | 1999-02-11 | — | — | WO | disclosed |
| WO-1999005189-A1 | POLYMERIZATION OF OLEFINS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-02-04 | — | — | WO | disclosed |
| US-5834136-A | POLYMERIC MATRICES FOR NONAQUEOUS ELECTROCHEMICAL CELLS | VALENCE TECHNOLOGY, INC. (US) | 1998-11-10 | — | — | US | disclosed |
| WO-1997049137-A1 | METHOD OF PREPARING POLYMERIC ELECTROLYTES | VALENCE TECHNOLOGY, INC. (US) | 1997-12-24 | — | — | WO | disclosed |
| EP-0763015-A1 | SYSTEMATIC MODULAR PRODUCTION OF AMINIMIDE- AND OXAZOLONE- BASED MOLECULES HAVING AT LEAST TWO STRUCTURAL DIVERSITY ELEMENTS | ARQULE, INC. (US) | 1997-03-19 | — | — | EP | disclosed |
| US-5391580-A | Polymer layer directly attached to polypropylene tube and active heparin linked through covalent bond to the layer | ANATRACE INC. (US) | 1995-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088788-A1 | SUBSTITUTED IMIDAZOLES AS BOMBESIN RECEPTOR SUBTYPE-3 MODULATORS | BRS3, GPR119, GIPR | HMGCR 4611/4885CHRM1 558/4885TBXA2R 461/4885 |
| US-20100004280-A1 | Substituted imidazoles as bombesin receptor subtype-3 modulators | BRS3, GPR119, GIPR | HMGCR 4611/4885CHRM1 558/4885TBXA2R 461/4885 |
| US-20100022598-A1 | Substituted inmidazoles as bombesin receptor subtype-3 modulators | BRS3, INSR, INSRR | HMGCR 4609/4885CHRM1 928/4885TBXA2R 607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.