Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.39 |
| ▸ | PGK2 | P07205 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 16/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 9/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1251782 | 0.83 | SLC6A4 (0.43) | PGK1PGK2SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL20231823 | 0.83 | PGK1 (0.50) | PGK1PGK2NOS3NOS1NOS2 | |
| SCHEMBL14036682 | 0.79 | SLC6A4 (0.37) | SLC6A4SLC6A2SLC6A3NOS3NOS1 | |
| SCHEMBL599112 | 0.75 | NOS3 (0.44) | PGK1PGK2NOS3NOS1NOS2 | |
| SCHEMBL5830801 | 0.75 | NOS3 (0.44) | PGK1PGK2NOS3NOS1NOS2 | |
| SCHEMBL14036540 | 0.74 | CYP1A2 (0.41) | SLC6A4ALDH1A1KDM4EKCNH2 | |
| SCHEMBL14035670 | 0.72 | HTR7 (0.41) | SLC6A4SLC6A2SLC6A3NOS3NOS1 | |
| SCHEMBL22702981 | 0.72 | HTR7 (0.45) | SLC6A4SLC6A2SLC6A3NOS3NOS1 | |
| SCHEMBL14496813 | 0.71 | PGK1 (0.41) | PGK1PGK2NOS3NOS1NOS2 | |
| SCHEMBL5013657 | 0.71 | NOS3 (0.43) | PGK1PGK2NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008137102-A2 | METHODS OF MODULATING AMYLOID BETA AND COMPOUNDS USEFUL THEREFOR | TORREYPINES THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |
| WO-2008137102-A2 | METHODS OF MODULATING AMYLOID BETA AND COMPOUNDS USEFUL THEREFOR | TORREYPINES THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |