SCHEMBL5830801

SCHEMBL5830801

CCc1cc(CC)c(CC)cc1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 1/20 0.44
NOS1 P29475 1/20 0.44
NOS2 P35228 1/20 0.44
PGK1 P00558 1/20 0.42
PGK2 P07205 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
ALDH1A1 P00352 3/20 0.40
GRIN2D O15399 1/20 0.40
GRIN3B O60391 1/20 0.40
GRIN1 Q05586 1/20 0.40
GRIN2A Q12879 1/20 0.40
GRIN2B Q13224 1/20 0.40
GRIN2C Q14957 1/20 0.40
GRIN3A Q8TCU5 1/20 0.40
ALOX15 P16050 2/20 0.36
ALOX12 P18054 1/20 0.36
CYP1A2 P05177 1/20 0.35
CASP7 P55210 1/20 0.35
HIF1A Q16665 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20231823 0.90 PGK1 (0.50) NOS3NOS1NOS2PGK1PGK2
SCHEMBL599112 0.88 NOS3 (0.44) NOS3NOS1NOS2PGK1PGK2
SCHEMBL9770020 0.87 GRIN2D (0.43) NOS3NOS1NOS2PGK1PGK2
SCHEMBL3205225 0.83 GRIN2D (0.50) NOS3NOS1NOS2PGK1PGK2
SCHEMBL15760672 0.82 NPSR1 (0.36) NOS3NOS1NOS2PGK1PGK2
SCHEMBL13879978 0.80 NOS3 (0.45) NOS3NOS1NOS2PGK1PGK2
SCHEMBL22739843 0.78 ALOX15 (0.37) NOS3NOS1NOS2ALDH1A1ALOX15
SCHEMBL11513154 0.78 ALDH1A1 (0.50) NOS3NOS1NOS2PGK1PGK2
SCHEMBL11076422 0.78 NPSR1 (0.50) NOS3NOS1NOS2NPSR1ALDH1A1
SCHEMBL5013657 0.78 NOS3 (0.43) NOS3NOS1NOS2PGK1PGK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9249091-B2 Post-treated sulfurized salt of an alkyl-substituted hydroxyaromatic composition CHEVRON ORONITE COMPANY LLC (US) 2016-02-02 US claimed
US-20130165359-A1 POST-TREATED SULFURIZED SALT OF AN ALKYL-SUBSTITUTED HYDROXYAROMATIC COMPOSITION CHEVRON ORONITE COMPANY LLC (US) 2013-06-27 US claimed
US-7056986-B2 ethylene monomer can be a vinyl ketone, ether, ester, halide, nitrile, aromatic, or an allyl ether; acrylic monomer can be a mono- or diacid or monoester of a diacid; a monoamine, a guanidine compound, and an aromatic diamine; improved vulcanizability, balance between processability and compression set DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2006-06-06 US claimed
CN-108774561-B Sulfurized salts of post-treated alkyl-substituted hydroxyaromatic compositions 雪佛龙奥伦耐有限责任公司 2022-07-01 CN disclosed
EP-2798050-B1 POST-TREATED SULFURIZED SALT OF AN ALKYL-SUBSTITUTED HYDROXYAROMATIC COMPOSITION CHEVRON ORONITE CO (US) 2020-04-22 EP disclosed
EP-3045309-A1 DUCTILE METAL LAMINATE AND METHOD OF MANUFACTURING SAME LG Chem, Ltd. (KR) 2016-07-20 EP disclosed
US-9249091-B2 Post-treated sulfurized salt of an alkyl-substituted hydroxyaromatic composition CHEVRON ORONITE COMPANY LLC (US) 2016-02-02 US disclosed
CN-103998586-A Sulfurized salts of post-treated alkyl-substituted hydroxyaromatic compositions CHEVRON ORONITE CO 2014-08-20 CN disclosed
EP-1449881-B1 ACRYLIC RUBBER COMPOSITION DENKI KAGAKU KOGYO KK (JP) 2014-06-18 EP disclosed
US-20130165359-A1 POST-TREATED SULFURIZED SALT OF AN ALKYL-SUBSTITUTED HYDROXYAROMATIC COMPOSITION CHEVRON ORONITE COMPANY LLC (US) 2013-06-27 US disclosed
US-7056986-B2 ethylene monomer can be a vinyl ketone, ether, ester, halide, nitrile, aromatic, or an allyl ether; acrylic monomer can be a mono- or diacid or monoester of a diacid; a monoamine, a guanidine compound, and an aromatic diamine; improved vulcanizability, balance between processability and compression set DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2006-06-06 US disclosed
US-20040266922-A1 Ethylene-acrylic copolymer rubber composition DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2004-12-30 US disclosed
EP-1449881-A1 ACRYLIC RUBBER COMPOSITION DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2004-08-25 EP disclosed
US-6084109-A GAS PHASE OXIDATION AND DEHYDRATION OF A 1,2,4,5-TETRAALKYL-BENZENE UNDER NORMAL PRESSURE AND HEATING USING A DURABLE, THERMOCONDUCTIVE CATALYST SYSTEM OF A CATALYST SUPPORT OF TUNGSTEN AND/OR SILICON CARBIDE CHINESE PETROLEUM CORP. (TW) 2000-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130165359-A1 POST-TREATED SULFURIZED SALT OF AN ALKYL-SUBSTITUTED HYDROXYAROMATIC COMPOSITION TST, PAH, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 NOS3 488/4885NOS1 678/4885NOS2 750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.