SCHEMBL5023948

SCHEMBL5023948

C[SiH2]OC(Cc1ccccc1N)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.33
TDO2 P48775 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNA4 P43681 1/20 0.33
OPRK1 P41145 1/20 0.32
HPGD P15428 1/20 0.32
TAAR1 Q96RJ0 2/20 0.32
SIGMAR1 Q99720 1/20 0.31
NOS2 P35228 1/20 0.31
SLC6A4 P31645 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4171307 0.78 SIGMAR1 (0.42) OPRK1TAAR1SIGMAR1SLC6A4
SCHEMBL5023592 0.77 SOAT1 (0.41) CHRNB2CHRNA4TAAR1SIGMAR1SLC6A4
SCHEMBL5024553 0.74 MAOB (0.45) IDO1TDO2OPRK1TAAR1SIGMAR1
SCHEMBL9646578 0.72 AOC3 (0.47) SLC6A4
SCHEMBL28642465 0.70 MAPT (0.36) OPRK1HPGDSLC6A4
SCHEMBL9054723 0.70 GRIN2D (0.47) TAAR1
Hydrochloric Acid SCHEMBL9582478 0.68 GRIN2D (0.46)
SCHEMBL105302 0.68 DPP4 (0.45) TAAR1SIGMAR1SLC6A4
SCHEMBL9001661 0.68 ALDH1A1 (0.42) TAAR1SIGMAR1
SCHEMBL10350443 0.68 ATM (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240274848-A1 FLUORINATED IONOMERS, POLYMER ELECTROLYTE MEMBRANES, FUEL CELLS, AND METHODS COLORADO SCHOOL OF MINES 2024-08-15 US disclosed
WO-2022256669-A1 FLUORINATED IONOMERS, POLYMER ELECTROLYTE MEMBRANES, FUEL CELLS, AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-12-08 WO disclosed
US-9240287-B2 Immobilized heteropoly acids and the use of the same electrode stabilization and enhancement COLORADO SCHOOL OF MINES (US) 2016-01-19 US disclosed
US-20140234750-A1 IMMOBILIZED HETEROPOLY ACIDS AND THE USE OF THE SAME FOR ELECTRODE STABILIZATION AND ENHANCEMENT COLORADO SCHOOL OF MINES (US) 2014-08-21 US disclosed
US-8753997-B2 Immobilized heteropoly acids and the use of the same for electrode stabilization and enhancement COLORADO SCHOOL OF MINES (US) 2014-06-17 US disclosed
US-20080299433-A1 IMMOBILIZED HETEROPOLY ACIDS AND THE USE OF THE SAME FOR ELECTRODE STABILIZATION AND ENHANCEMENT COLORADO SCHOOL OF MINES 2008-12-04 US disclosed