SCHEMBL5023595

SCHEMBL5023595

C[SiH2]OC(C)c1ccccc1-c1ccc(N)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40
NCOA1 Q15788 1/20 0.36
NCOA3 Q9Y6Q9 1/20 0.36
CYP3A4 P08684 3/20 0.35
TDP1 Q9NUW8 3/20 0.35
TAAR1 Q96RJ0 1/20 0.35
HSD17B10 Q99714 1/20 0.35
PPARA Q07869 2/20 0.32
PPARG P37231 1/20 0.32
ALOX5AP P20292 1/20 0.32
FEN1 P39748 1/20 0.32
PRKCZ Q05513 1/20 0.32
ALDH1A1 P00352 2/20 0.31
TP53 P04637 2/20 0.31
KIT P10721 2/20 0.30
KDR P35968 2/20 0.30
FLT3 P36888 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5024557 0.83 ADRA2A (0.43) CYP3A4ALOX5APFEN1ALDH1A1TP53
SCHEMBL5023950 0.80 ALDH1A1 (0.45) CYP3A4TDP1HSD17B10ALDH1A1TP53
SCHEMBL2787589 0.77 CA1 (0.61) CA12CA1CA2CA9NCOA1
SCHEMBL6742476 0.74 CA12 (0.45) CA12CA1CA2CA9NCOA1
SCHEMBL7671735 0.69 CA1 (0.44) CA12CA1CA2CA9NCOA1
Ethane SCHEMBL28326373 0.68 CYP3A4 (0.57) NCOA1NCOA3CYP3A4TDP1TAAR1
SCHEMBL8637586 0.67 CYP3A4 (0.42) CA12CA1CA2CA9NCOA1
SCHEMBL9246341 0.67 HSD17B10 (0.63) NCOA1NCOA3CYP3A4TDP1TAAR1
SCHEMBL6014197 0.67 ACHE (0.62) NCOA1NCOA3CYP3A4TDP1TAAR1
SCHEMBL28977901 0.66 CA1 (0.44) CA12CA1CA2CA9CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240274848-A1 FLUORINATED IONOMERS, POLYMER ELECTROLYTE MEMBRANES, FUEL CELLS, AND METHODS COLORADO SCHOOL OF MINES 2024-08-15 US disclosed
US-9240287-B2 Immobilized heteropoly acids and the use of the same electrode stabilization and enhancement COLORADO SCHOOL OF MINES (US) 2016-01-19 US disclosed
US-20140234750-A1 IMMOBILIZED HETEROPOLY ACIDS AND THE USE OF THE SAME FOR ELECTRODE STABILIZATION AND ENHANCEMENT COLORADO SCHOOL OF MINES (US) 2014-08-21 US disclosed
US-8753997-B2 Immobilized heteropoly acids and the use of the same for electrode stabilization and enhancement COLORADO SCHOOL OF MINES (US) 2014-06-17 US disclosed
US-20080299433-A1 IMMOBILIZED HETEROPOLY ACIDS AND THE USE OF THE SAME FOR ELECTRODE STABILIZATION AND ENHANCEMENT COLORADO SCHOOL OF MINES 2008-12-04 US disclosed