Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.40 |
| ▸ | ITGAV | P06756 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 3/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | OGA | O60502 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5025617 | 0.77 | ITGB3 (0.51) | ITGB3ITGAVMAPK1 | |
| SCHEMBL5879680 | 0.72 | ITGB3 (0.46) | ITGB3ITGAVMAPK1KDM4E | |
| SCHEMBL5025452 | 0.69 | LMNA (0.47) | ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL5025495 | 0.67 | MAPK1 (0.69) | ALDH1A1MAPK1TSHRSMN1; SMN2CCNE1 | |
| SCHEMBL5026331 | 0.61 | CA12 (0.39) | ALDH1A1MEN1KMT2A | |
| SCHEMBL5024045 | 0.58 | PSEN1 (0.39) | ALDH1A1L3MBTL1MAPK1TSHRSMN1; SMN2 | |
| SCHEMBL10959901 | 0.58 | AOC3 (0.37) | ALDH1A1L3MBTL1MAPK1TSHRSMN1; SMN2 | |
| SCHEMBL5029851 | 0.58 | ITGB3 (0.65) | ALDH1A1L3MBTL1ITGB3ITGAVMAPK1 | |
| Hydrochloric Acid SCHEMBL5024024 | 0.57 | PSEN1 (0.39) | ALDH1A1L3MBTL1MAPK1TSHRSMN1; SMN2 | |
| SCHEMBL6335118 | 0.57 | MAPK13 (0.56) | ALDH1A1TSHRSMN1; SMN2CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221082-A1 | Ligands of Integrin Receptors | ABBOTT GMBH & CO. KG (DE) | 2008-09-11 | — | — | US | disclosed |
| EP-1286673-B1 | LIGANDS OF INTEGRIN RECEPTORS | BASF AG (DE) | 2005-05-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221082-A1 | Ligands of Integrin Receptors | ITGB3, ITGAV, ITGA2B | ALDH1A1 2222/4885HSD17B10 4617/4885L3MBTL1 3809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.