Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.46 |
| ▸ | ITGAV | P06756 | 14/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879621 | 0.85 | ITGB3 (0.51) | ITGB3ITGAVMAPK1KDM4ETHRB | |
| SCHEMBL5879553 | 0.85 | ITGB3 (0.47) | ITGB3ITGAVKDM4E | |
| SCHEMBL5879582 | 0.75 | ITGB3 (0.74) | ITGB3ITGAV | |
| SCHEMBL5879645 | 0.74 | ITGB3 (0.61) | ITGB3ITGAVKDM4E | |
| SCHEMBL5879558 | 0.73 | ITGB3 (0.74) | ITGB3ITGAVKDM4ETHRB | |
| SCHEMBL5879569 | 0.73 | ITGB3 (0.51) | ITGB3ITGAVMAPK1KDM4ETHRB | |
| SCHEMBL5879698 | 0.73 | ITGB3 (0.71) | ITGB3ITGAV | |
| SCHEMBL5023980 | 0.72 | ALDH1A1 (0.40) | ITGB3ITGAVMAPK1KDM4E | |
| SCHEMBL5879625 | 0.71 | ITGB3 (0.61) | ITGB3ITGAVKDM4E | |
| SCHEMBL5879791 | 0.70 | ITGB3 (0.74) | ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |