SCHEMBL502432

SCHEMBL502432

CCO[Si](OCC)(OCC)C(CC)N(Br)C(C)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19970538 0.80 ALDH1A1 (0.31)
SCHEMBL15796950 0.72 THRB (0.35)
SCHEMBL2566448 0.71 ALOX15 (0.33)
SCHEMBL555039 0.69
SCHEMBL443028 0.69 ALDH1A1 (0.30)
SCHEMBL10863724 0.69 ALOX15 (0.32)
SCHEMBL16390384 0.68
SCHEMBL514548 0.68
SCHEMBL11118295 0.67 ALDH1A1 (0.33)
SCHEMBL3338570 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11781184-B2 Method for sequencing a polynucleotide template ILLUMINA CAMBRIDGE LIMITED (GB) 2023-10-10 US disclosed
US-20230193384-A1 METHOD FOR SEQUENCING A POLYNUCLEOTIDE TEMPLATE ILLUMINA CAMBRIDGE LIMITED (GB) 2023-06-22 US disclosed
US-20220254443-A1 SYSTEM AND METHODS FOR DETECTING GENETIC VARIATION MYRIAD WOMEN'S HEALTH, INC. (US) 2022-08-11 US disclosed
US-10876158-B2 Method for sequencing a polynucleotide template ILLUMINA CAMBRIDGE LIMITED (GB) 2020-12-29 US disclosed
EP-1987159-B2 METHOD FOR SEQUENCING A POLYNUCLEOTIDE TEMPLATE ILLUMINA CAMBRIDGE LTD (GB) 2020-08-12 EP disclosed
US-20200216896-A1 METHOD FOR SEQUENCING A POLYNUCLEOTIDE TEMPLATE ILLUMINA CAMBRIDGE LIMITED (GB) 2020-07-09 US disclosed
EP-3670672-A1 METHOD FOR SEQUENCING A POLYNUCLEOTIDE TEMPLATE Illumina Cambridge Limited (GB) 2020-06-24 EP disclosed
US-10563256-B2 Method for sequencing a polynucleotide template ILLUMINA CAMBRIDGE LIMITED (GB) 2020-02-18 US disclosed
US-10221452-B2 Method for pairwise sequencing of target polynucleotides ILLUMINA CAMBRIDGE LIMITED (GB) 2019-03-05 US disclosed
US-20180363047-A1 METHOD FOR SEQUENCING A POLYNUCLEOTIDE TEMPLATE ILLUMINA CAMBRIDGE LIMITED (GB) 2018-12-20 US disclosed
EP-2191011-A1 METHOD FOR SEQUENCING A POLYNUCLEOTIDE TEMPLATE Illumina Cambridge (GB) 2010-06-02 EP disclosed
CN-101663405-A Method for sequencing a polynucleotide template SOLEXA LTD 2010-03-03 CN disclosed
US-20090181370-A1 Method for Sequencing a Polynucleotide Template ILLUMINA CAMBRIDGE LIMITED (GB) 2009-07-16 US disclosed
CN-101415839-A Method for sequencing a polynucleotide template SOLEXA LTD (GB) 2009-04-22 CN disclosed
US-20090093378-A1 Method for sequencing a polynucleotide template ILLUMINA CAMBRIDGE LIMITED (GB) 2009-04-09 US disclosed
US-20090088327-A1 Method for sequencing a polynucleotide template SOLEXA LIMITED (GB) 2009-04-02 US disclosed
WO-2009032167-A1 METHOD FOR SEQUENCING A POLYNUCLEOTIDE TEMPLATE ILLUMINA CAMBRIDGE (GB) 2009-03-12 WO disclosed
US-20080108515-A1 Arrayed polynucleotides ILLUMINA CAMBRIDGE LIMITED (GB) 2008-05-08 US disclosed
EP-1716251-A1 ARRAYED POLYNUCLEOTIDES Solexa Limited (GB) 2006-11-02 EP disclosed
WO-2005078130-A1 ARRAYED POLYNUCLEOTIDES SOLEXA LIMITED (GB) 2005-08-25 WO disclosed