Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR3 | O60755 | 1/20 | 0.47 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.38 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12844622 | 0.88 | GALR3 (0.44) | GALR3NR2F2ALDH1A1TDP1MAPK8 | |
| SCHEMBL3163857 | 0.83 | ALDH1A1 (0.44) | GALR3NR2F2ALDH1A1TDP1MAPK8 | |
| SCHEMBL1467720 | 0.83 | MAPK8 (0.47) | GALR3NR2F2ALDH1A1TDP1MAPK8 | |
| SCHEMBL18885134 | 0.83 | ALDH1A1 (0.47) | GALR3NR2F2ALDH1A1TDP1MAPK8 | |
| SCHEMBL418824 | 0.82 | ALDH1A1 (0.50) | GALR3NR2F2ALDH1A1TDP1MAPK8 | |
| SCHEMBL5018871 | 0.82 | GALR3 (0.42) | GALR3NR2F2ALDH1A1TDP1MAPK8 | |
| SCHEMBL12775849 | 0.82 | GALR3 (0.47) | GALR3NR2F2ALDH1A1TDP1MAPK8 | |
| Hydrochloric Acid SCHEMBL2460792 | 0.81 | MAPK8 (0.46) | GALR3NR2F2ALDH1A1TDP1MAPK8 | |
| SCHEMBL18317380 | 0.81 | ALDH1A1 (0.55) | GALR3NR2F2ALDH1A1TDP1MAPK8 | |
| SCHEMBL1620477 | 0.79 | SMPD1 (0.45) | GALR3NR2F2ALDH1A1TDP1MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11236082-B2 | EZH2 inhibitors and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-02-01 | — | — | US | disclosed |
| US-20170349587-A1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | SHIONOGI & CO., LTD. (JP) | 2017-12-07 | — | — | US | disclosed |
| US-9815835-B2 | Substituted polycyclic carbamolypyridone derivative | SHIONOGI & CO., LTD. (JP) | 2017-11-14 | — | — | US | disclosed |
| EP-2794611-B1 | PYRAZOLO[1,5-A]PYRIMIDINES AS ANTIVIRAL AGENTS | GILEAD SCIENCES INC (US) | 2017-10-11 | — | — | EP | disclosed |
| US-9758515-B2 | Substituted polycyclic carbamoyl pyridone derivative prodrug | SHIONOGI & CO., LTD. (JP) | 2017-09-12 | — | — | US | disclosed |
| US-20170216283-A1 | COMPOUNDS AND USES | ASTRAZENECA AB (SE) | 2017-08-03 | — | — | US | disclosed |
| US-20170216283-A1 | COMPOUNDS AND USES | ASTRAZENECA AB (SE) | 2017-08-03 | — | — | US | disclosed |
| US-9657001-B2 | Compounds and uses | ASTRAZENECA AB (SE) | 2017-05-23 | — | — | US | disclosed |
| US-9657001-B2 | Compounds and uses | ASTRAZENECA AB (SE) | 2017-05-23 | — | — | US | disclosed |
| US-20160368921-A1 | SUBSTITUTED POLYCYCLIC CARBAMOLYPYRIDONE DERIVATIVE | SHIONOGI & CO (JP) | 2016-12-22 | — | — | US | disclosed |
| US-20110306597-A1 | Nicotinamide Derivatives | CRAWFORTH JAMES MICHAEL (GB) | 2011-12-15 | — | — | US | disclosed |
| US-20100215735-A1 | Compounds for Inhibiting Beta-Amyloid Production and Methods of Identifying the Compounds | MULLAN MICHAEL J | 2010-08-26 | — | — | US | disclosed |
| US-20100152098-A1 | POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | MPEX PHARMACEUTICALS, INC. (US) | 2010-06-17 | — | — | US | disclosed |
| WO-2009153721-A1 | NICOTINAMIDE DERIVATIVES | PFIZER LIMITED (GB) | 2009-12-23 | — | — | WO | disclosed |
| US-20080058330-A1 | Compounds and Combinations Thereof for Inhibiting Beta-Amyloid Production and Methods of Use Thereof | ROSKAMP RESEARCH LLC (US) | 2008-03-06 | — | — | US | disclosed |
| US-7338959-B2 | Diamino-pyrimidines and their use as angiogenesis inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2008-03-04 | — | — | US | disclosed |
| US-7338959-B2 | Diamino-pyrimidines and their use as angiogenesis inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2008-03-04 | — | — | US | disclosed |
| US-20070185130-A1 | Compounds for inhibiting beta-amyloid production and methods of identifying the compounds | ROSKAMP RESEARCH LLC | 2007-08-09 | — | — | US | disclosed |
| EP-1487824-B1 | DIAMINO-PYRIMIDINES AND THEIR USE AS ANGIOGENESIS INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2007-06-20 | — | — | EP | disclosed |
| US-20070037855-A1 | Compounds for inhibiting beta-amyloid production and methods of identifying the compounds | ALZHEIMER'S INSTITUTE OF AMERICA, INC. | 2007-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170216283-A1 | COMPOUNDS AND USES | LTC4S, LTB4R2, LTA4H | GALR3 769/4885NR2F2 3313/4885ALDH1A1 268/4885 |
| US-20160368921-A1 | SUBSTITUTED POLYCYCLIC CARBAMOLYPYRIDONE DERIVATIVE | CNBP, ZC3HAV1, DPP4 | GALR3 3884/4885NR2F2 2379/4885ALDH1A1 1937/4885 |
| US-20080058330-A1 | Compounds and Combinations Thereof for Inhibiting Beta-Amyloid Production and Methods of Use Thereof | APP, PSEN1, PSEN2 | GALR3 2635/4885NR2F2 1929/4885ALDH1A1 3749/4885 |
| US-20070185130-A1 | Compounds for inhibiting beta-amyloid production and methods of identifying the compounds | APP, PSEN1, PSEN2 | GALR3 2543/4885NR2F2 2130/4885ALDH1A1 3939/4885 |
| US-20070037855-A1 | Compounds for inhibiting beta-amyloid production and methods of identifying the compounds | APP, PSEN1, PSEN2 | GALR3 2543/4885NR2F2 2130/4885ALDH1A1 3939/4885 |
| US-20100152098-A1 | POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | ABCB11, ABCB1, SLC47A1 | GALR3 4680/4885NR2F2 4113/4885ALDH1A1 4062/4885 |
| US-20110306597-A1 | Nicotinamide Derivatives | NNT, NAMPT, NQO1 | GALR3 889/4885NR2F2 972/4885ALDH1A1 172/4885 |
| US-20170349587-A1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | PREP, UNG, DPP4 | GALR3 4213/4885NR2F2 3167/4885ALDH1A1 1564/4885 |
| US-20100215735-A1 | Compounds for Inhibiting Beta-Amyloid Production and Methods of Identifying the Compounds | APP, PSEN1, PSEN2 | GALR3 2543/4885NR2F2 2130/4885ALDH1A1 3939/4885 |
| US-11236082-B2 | EZH2 inhibitors and uses thereof | EZH2, EZH1, BMI1 | GALR3 4430/4885NR2F2 747/4885ALDH1A1 1655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.