Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.44 |
| ▸ | RARA | P10276 | 1/20 | 0.44 |
| ▸ | RARG | P13631 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL503169 | 0.90 | RARB (0.43) | RARBRARARARGMCL1CA2 | |
| SCHEMBL6519497 | 0.89 | RARB (0.58) | RARBRARARARGCA2TP53 | |
| SCHEMBL502476 | 0.82 | RARB (0.47) | RARBRARARARGMCL1NPC1 | |
| SCHEMBL6409307 | 0.81 | RARB (0.43) | RARBRARARARGMCL1CA2 | |
| SCHEMBL9764255 | 0.80 | RARB (0.46) | RARBRARARARGMCL1CA2 | |
| SCHEMBL16258127 | 0.80 | RARB (0.46) | RARBRARARARGMCL1CA2 | |
| SCHEMBL14525745 | 0.80 | RARB (0.46) | RARBRARARARGMCL1CA2 | |
| SCHEMBL10030242 | 0.79 | RARB (0.54) | RARBRARARARGCA2HSD17B10 | |
| SCHEMBL16080727 | 0.79 | RARB (0.45) | RARBRARARARGMCL1CA2 | |
| SCHEMBL19844721 | 0.79 | RARB (0.45) | RARBRARARARGMCL1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8916718-B2 | Compound having 2-fluorophenyloxymethane structure | DIC CORPORATION (JP) | 2014-12-23 | — | — | US | disclosed |
| US-8916718-B2 | Compound having 2-fluorophenyloxymethane structure | DIC CORPORATION (JP) | 2014-12-23 | — | — | US | disclosed |
| US-20140275577-A1 | COMPOUND HAVING 2-FLUOROPHENYLOXYMETHANE STRUCTURE | DIC CORPORATION (JP) | 2014-09-18 | — | — | US | disclosed |
| US-20140275577-A1 | COMPOUND HAVING 2-FLUOROPHENYLOXYMETHANE STRUCTURE | DIC CORPORATION (JP) | 2014-09-18 | — | — | US | disclosed |
| EP-2123623-B1 | LIQUID CRYSTALLINE COMPOUND, LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT | JNC CORP (JP) | 2013-08-07 | — | — | EP | disclosed |
| US-7846514-B2 | Liquid crystal compound, liquid crystal composition and, liquid crystal display device | CHISSO CORPORATION (JP) | 2010-12-07 | — | — | US | disclosed |
| US-7846514-B2 | Liquid crystal compound, liquid crystal composition and, liquid crystal display device | CHISSO CORPORATION (JP) | 2010-12-07 | — | — | US | disclosed |
| US-7846514-B2 | Liquid crystal compound, liquid crystal composition and, liquid crystal display device | CHISSO CORPORATION (JP) | 2010-12-07 | — | — | US | disclosed |
| US-20100073621-A1 | LIQUID CRYSTALLINE COMPOUND, LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT | CHISSO CORPORATION (JP) | 2010-03-25 | — | — | US | disclosed |
| US-20100073621-A1 | LIQUID CRYSTALLINE COMPOUND, LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT | CHISSO CORPORATION (JP) | 2010-03-25 | — | — | US | disclosed |
| US-20100073621-A1 | LIQUID CRYSTALLINE COMPOUND, LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT | CHISSO CORPORATION (JP) | 2010-03-25 | — | — | US | disclosed |
| EP-2123623-A1 | LIQUID CRYSTALLINE COMPOUND, LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT | Chisso Corporation (JP) | 2009-11-25 | — | — | EP | disclosed |
| EP-2123623-A1 | LIQUID CRYSTALLINE COMPOUND, LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT | Chisso Corporation (JP) | 2009-11-25 | — | — | EP | disclosed |
| US-6864397-B2 | Difluoromethyl ether derivative and process for producing the same | CHISSO CORPORATION (JP) | 2005-03-08 | — | — | US | disclosed |
| US-6827876-B2 | Using alpha, alpha -difluorocyclohexylidene derivative as starting material to obtain difluoromethyl ether derivative | CHISSO CORPORATION (JP) | 2004-12-07 | — | — | US | disclosed |
| US-20040016906-A1 | Difluoromethyl ether derivative and process for producing the same | JNC CORPORATION (JP) | 2004-01-29 | — | — | US | disclosed |
| US-20040004207-A1 | Difluoromethyl ether derivative and process for producing the same | JNC CORPORATION (JP) | 2004-01-08 | — | — | US | disclosed |
| US-6605747-B2 | Reacting the starting material, an alpha , alpha -difluorocyclohexylidene derivative with a halogen to produce an intermediate, reacting the intermediate with a phenol compound in presence of a base | CHISSO CORPORATION (JP) | 2003-08-12 | — | — | US | disclosed |
| US-20020120168-A1 | Difluoromethyl ether derivative and process for producing the same | JNC PETROCHEMICAL CORPORATION (JP) | 2002-08-29 | — | — | US | disclosed |
| EP-1182186-A2 | Difluoromethyl ether derivative and process for producing the same | CHISSO CORPORATION (JP) | 2002-02-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040004207-A1 | Difluoromethyl ether derivative and process for producing the same | RCC1, PYM1, SCFD1 | RARB 3277/4885RARA 2698/4885RARG 3554/4885 |
| US-20140275577-A1 | COMPOUND HAVING 2-FLUOROPHENYLOXYMETHANE STRUCTURE | PIK3CD, TEC, PIK3C3 | RARB 4494/4885RARA 3939/4885RARG 4409/4885 |
| US-20100073621-A1 | LIQUID CRYSTALLINE COMPOUND, LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT | TRPV4, TRPV5, ZKSCAN2 | RARB 2425/4885RARA 2650/4885RARG 3171/4885 |
| US-20040016906-A1 | Difluoromethyl ether derivative and process for producing the same | RCC1, SCFD1, AFF1 | RARB 3298/4885RARA 2721/4885RARG 3614/4885 |
| US-20020120168-A1 | Difluoromethyl ether derivative and process for producing the same | LEF1, AFF1, RCC1 | RARB 2584/4885RARA 2060/4885RARG 2720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.