SCHEMBL5025844

SCHEMBL5025844

Cc1ccc(N(CC(O)c2ccc(-c3ccccc3)cc2)c2ccc(C)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 2/20 0.44
UTS2R Q9UKP6 2/20 0.40
SLC6A2 P23975 2/20 0.40
SLC6A4 P31645 2/20 0.40
TAAR1 Q96RJ0 1/20 0.39
FAAH O00519 1/20 0.39
LMNA P02545 2/20 0.38
KDM4E B2RXH2 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
POLB P06746 1/20 0.38
APOBEC3A P31941 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
SLC6A3 Q01959 1/20 0.38
PTGS2 P35354 1/20 0.38
CYP2C19 P33261 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13241976 0.74 CYP2C19 (0.46) TAAR1LMNAKDM4EL3MBTL1POLB
SCHEMBL18642753 0.74 HTR2A (0.52) SLC6A2SLC6A4LMNAKDM4EL3MBTL1
SCHEMBL5025865 0.73 UTS2R (0.38) UTS2RKDM4EL3MBTL1POLBCYP3A4
SCHEMBL5025843 0.73 UTS2R (0.41) UTS2RSLC6A2SLC6A4PTGS2CYP2C19
SCHEMBL19152522 0.73 MMP12 (0.50) UTS2RLMNAL3MBTL1
SCHEMBL21969920 0.72 KDM4E (0.51) SLC6A2SLC6A4KDM4EL3MBTL1POLB
SCHEMBL13241961 0.71 CYP2C19 (0.61) TAAR1LMNAKDM4EPOLBCYP2C19
SCHEMBL20414248 0.71 MEN1 (0.40) UTS2RLMNAKDM4EL3MBTL1POLB
SCHEMBL17735825 0.71 CYP2C19 (0.61) TAAR1LMNAKDM4EPOLBCYP2C19
SCHEMBL13338509 0.71 SMN1; SMN2 (0.41) UTS2RLMNAKDM4EL3MBTL1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080304867-A1 Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge RICOH COMPANY, LTD. 2008-12-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080304867-A1 Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge KDM1A, C9, JMJD6 AOC3 1713/4885UTS2R 2372/4885SLC6A2 2223/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.