SCHEMBL5025843

SCHEMBL5025843

Cc1ccc(N(c2ccc(C)cc2)C(CO)c2ccc(-c3ccccc3)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 3/20 0.41
ACP3 P15309 2/20 0.39
PTGS2 P35354 1/20 0.39
CYP2C19 P33261 1/20 0.39
NR1H2 P55055 3/20 0.38
NR1H3 Q13133 3/20 0.38
TP53 P04637 1/20 0.38
MAPT P10636 1/20 0.38
PTGES O14684 1/20 0.38
ALOX5 P09917 1/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
FFAR1 O14842 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
CHRNB2 P17787 1/20 0.37
CHRNA4 P43681 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28914293 0.77 NR1H2 (0.43) NR1H2NR1H3TP53MAPTSLC6A2
SCHEMBL13338509 0.75 SMN1; SMN2 (0.41) UTS2RPTGS2CYP2C19MAPTPTGES
SCHEMBL5025865 0.75 UTS2R (0.38) UTS2RPTGS2CYP2C19MAPTMEN1
SCHEMBL5025844 0.73 AOC3 (0.44) UTS2RPTGS2CYP2C19SLC6A2SLC6A4
SCHEMBL20414248 0.73 MEN1 (0.40) UTS2RPTGS2CYP2C19MAPTMEN1
SCHEMBL15604396 0.71 PTGS2 (0.42) UTS2RPTGS2CYP2C19MEN1KMT2A
SCHEMBL19275129 0.71 PTGS2 (0.42) UTS2RPTGS2CYP2C19MEN1KMT2A
SCHEMBL13751264 0.70 RAB9A (0.47) CYP2C19MAPTPTGESALOX5MEN1
SCHEMBL14004001 0.70 RAB9A (0.47) CYP2C19MAPTPTGESALOX5MEN1
SCHEMBL17702105 0.70 RAB9A (0.47) CYP2C19MAPTPTGESALOX5MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080304867-A1 Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge RICOH COMPANY, LTD. 2008-12-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080304867-A1 Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge KDM1A, C9, JMJD6 UTS2R 2372/4885ACP3 4764/4885PTGS2 1309/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.