SCHEMBL5025865

SCHEMBL5025865

[CH2]C(c1ccc(-c2ccccc2)cc1)N(c1ccc(C)cc1)c1ccc(C)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
HPGD P15428 2/20 0.38
PTGS2 P35354 1/20 0.38
CYP2C19 P33261 1/20 0.38
NPC1 O15118 1/20 0.38
POLB P06746 1/20 0.38
NFKB1 P19838 1/20 0.38
RAB9A P51151 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CYP3A4 P08684 1/20 0.37
CHRNB2 P17787 1/20 0.36
CHRNA4 P43681 1/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
CHRNA7 P36544 1/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13338509 0.79 SMN1; SMN2 (0.41) UTS2RTDP1HPGDPTGS2CYP2C19
SCHEMBL20414248 0.76 MEN1 (0.40) UTS2RTDP1HPGDPTGS2CYP2C19
SCHEMBL691332 0.76 PTGS2 (0.54) PTGS2CYP3A4CHRNB2CHRNA4ALDH1A1
SCHEMBL19275129 0.75 PTGS2 (0.42) UTS2RTDP1HPGDPTGS2CYP2C19
SCHEMBL15604396 0.75 PTGS2 (0.42) UTS2RTDP1HPGDPTGS2CYP2C19
SCHEMBL5025843 0.75 UTS2R (0.41) UTS2RPTGS2CYP2C19CHRNB2CHRNA4
SCHEMBL804819 0.74 RAB9A (0.47) TDP1HPGDCYP2C19NPC1POLB
SCHEMBL13751264 0.74 RAB9A (0.47) TDP1HPGDCYP2C19NPC1POLB
SCHEMBL13241996 0.74 RAB9A (0.47) TDP1HPGDCYP2C19NPC1POLB
SCHEMBL10109503 0.74 RAB9A (0.47) TDP1HPGDCYP2C19NPC1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080304867-A1 Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge RICOH COMPANY, LTD. 2008-12-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080304867-A1 Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge KDM1A, C9, JMJD6 UTS2R 2372/4885TDP1 4562/4885HPGD 2767/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.