Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ACP3 | P15309 | 2/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42818 | 0.84 | — | — | |
| SCHEMBL316110 | 0.84 | — | — | |
| SCHEMBL1870280 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL10398523 | 0.81 | TDP1 (0.48) | ALDH1A1TAAR1 | |
| SCHEMBL28147710 | 0.81 | MIF (0.44) | ALDH1A1TAAR1 | |
| SCHEMBL27418689 | 0.81 | MIF (0.44) | ALDH1A1TAAR1 | |
| SCHEMBL9539624 | 0.81 | ESR1 (0.38) | — | |
| SCHEMBL27616490 | 0.79 | RXRA (0.49) | PTGS2CHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL20833031 | 0.79 | PTGS2 (0.58) | PTGS2CHRNB2CHRNA4CYP3A4ALDH1A1 | |
| SCHEMBL40528 | 0.79 | PTGS2 (0.58) | PTGS2CHRNB2CHRNA4CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991002714-A1 | AUTOMATED PEPTIDE DESIGN AND SYNTHESIS | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, UNITED STATES DEPARTMENT OF COMMERCE (US) | 1991-03-07 | — | — | WO | claimed |
| CN-105408344-B | Peptide-resin conjugates and uses thereof | 佩特雷化学和生物制药学实验室有限公司 | 2020-08-11 | — | — | CN | disclosed |
| WO-2015131100-A1 | LIGAND-CONTROLLED C(SP3)-H ARYLATION AND OLEFINATION IN SYNTHESIS OF UNNATURAL CHIRAL ALPHA AMINO ACIDS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2015-09-03 | — | — | WO | disclosed |
| US-20140343227-A1 | Diketopiperazine Forming Dipeptidyl Linker | LONZA AG (CH) | 2014-11-20 | — | — | US | disclosed |
| US-20140275463-A1 | ORGANOSILICON COMPOUND AND PRODUCTION PROCESS FOR THE SAME, AND POLYSILOXANE AND PRODUCTION PROCESS FOR THE SAME | CHISSO PETROCHEMICAL CORPORATION (JP) | 2014-09-18 | — | — | US | disclosed |
| US-8802819-B2 | Diketopiperazine forming dipeptidyl linker | LONZA LTD. (CH) | 2014-08-12 | — | — | US | disclosed |
| EP-1548020-B1 | SILICON COMPOUND | JNC CORP (JP) | 2014-07-23 | — | — | EP | disclosed |
| EP-2632936-A1 | DIKETOPIPERAZINE FORMING DIPEPTIDYL LINKER | Lonza Ltd (CH) | 2013-09-04 | — | — | EP | disclosed |
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |
| US-8367792-B2 | Polysiloxane compound and method of producing the same | JNC CORPORATION (JP) | 2013-02-05 | — | — | US | disclosed |
| WO-1998019693-A1 | COMBINATORIAL LIBRARIES OF CYCLIC UREA AND CYCLIC THIOUREA DERIVATIVES AND COMPOUNDS THEREIN | TREGA BIOSCIENCES, INC. (US) | 1998-05-14 | — | — | WO | disclosed |
| WO-1998017647-A1 | PIPERIDINE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 1998-04-30 | — | — | WO | disclosed |
| WO-1998007685-A1 | PREPARATION OF CYCLOHEXENE CARBOXYLATE DERIVATIVES | GILEAD SCIENCES, INC. (US) | 1998-02-26 | — | — | WO | disclosed |
| EP-0821690-A1 | NOVEL COMPOUNDS AND METHODS FOR THERAPY | Ustav Organicke Chemie A Biochemie Akademie Ved Ceske Republiky (CZ) | 1998-02-04 | — | — | EP | disclosed |
| WO-1997049723-A1 | CATIONIC LIPIDS FOR DELIVERY OF NUCLEIC ACID TO CELLS | GILEAD SCIENCES, INC. (US) | 1997-12-31 | — | — | WO | disclosed |
| EP-0789695-A2 | THIEPANE COMPOUNDS INHIBITING AND DETECTING HIV PROTEASE | GILEAD SCIENCES, INC. (US) | 1997-08-20 | — | — | EP | disclosed |
| WO-1997010221-A1 | SYNTHESIS OF QUINAZOLINONE LIBRARIES | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 1997-03-20 | — | — | WO | disclosed |
| EP-0759917-A1 | NOVEL SELECTIVE INHIBITORS OF VIRAL OR BACTERIAL NEURAMINIDASES | GILEAD SCIENCES, INC. (US) | 1997-03-05 | — | — | EP | disclosed |
| WO-1996026933-A9 | NOVEL SELECTIVE INHIBITORS OF VIRAL OR BACTERIAL NEURAMINIDASES | — | 1996-11-28 | — | — | WO | disclosed |
| WO-1991002714-A1 | AUTOMATED PEPTIDE DESIGN AND SYNTHESIS | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, UNITED STATES DEPARTMENT OF COMMERCE (US) | 1991-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275463-A1 | ORGANOSILICON COMPOUND AND PRODUCTION PROCESS FOR THE SAME, AND POLYSILOXANE AND PRODUCTION PROCESS FOR THE SAME | PIEZO1, PFAS, MCM6 | PTGS2 1191/4885CHRNB2 4422/4885CHRNA4 3975/4885 |
| US-20140343227-A1 | Diketopiperazine Forming Dipeptidyl Linker | FAP, IAPP, DNPEP | PTGS2 2525/4885CHRNB2 4341/4885CHRNA4 4328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.