SCHEMBL7753605

SCHEMBL7753605

O=C(Cl)Oc1cc(C(=O)O)cc(C(=O)O)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TPMT P51580 3/20 0.44
TTR P02766 1/20 0.41
CA12 O43570 3/20 0.41
CA1 P00915 3/20 0.41
CA2 P00918 3/20 0.41
CA7 P43166 3/20 0.41
CA9 Q16790 3/20 0.41
CA14 Q9ULX7 3/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
LCK P06239 1/20 0.40
FYN P06241 1/20 0.40
AKR1C3 P42330 1/20 0.39
CA3 P07451 2/20 0.39
CA4 P22748 2/20 0.39
CA6 P23280 2/20 0.39
CA5A P35218 2/20 0.39
CA5B Q9Y2D0 2/20 0.39
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5025919 0.95 TPMT (0.44) TPMTTTRCA12CA1CA2
SCHEMBL11702300 0.94 TPMT (0.40) TPMTTTRCA12CA1CA2
SCHEMBL11703054 0.88 CA12 (0.56) TPMTTTRCA12CA1CA2
SCHEMBL890486 0.84 POLB (0.31) ALDH1A1TSHRPOLB
SCHEMBL998315 0.80 KMT2A (0.39) TTRMEN1KMT2AKDM4EALDH1A1
SCHEMBL1259679 0.79 AKR1C3 (0.61) CA12CA1CA2CA9KMT2A
SCHEMBL17237455 0.79 KMT2A (0.37) MEN1KMT2AMAPTHPGDTDP1
SCHEMBL11699992 0.79 MEN1 (0.32) MEN1KMT2AALDH1A1TSHR
SCHEMBL1543332 0.77 HSD17B10 (0.57) TPMTTTRCA12CA1CA2
SCHEMBL11276120 0.74 TP53 (0.50) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0575870-B1 Process for producing aromatic polycarbonate MITSUI CHEMICALS INC (JP) 2001-01-31 EP disclosed
EP-0581074-B1 Processes for producing aromatic polycarbonate oligomer and aromatic polycarbonate MITSUI CHEMICALS INC (JP) 1999-03-10 EP disclosed
US-5380814-A Molecular weight control MITSUI TOATSU CHEMICALS, INC. (JP) 1995-01-10 US disclosed
US-5359117-A Continuous processing using molecular weight control agent, catalyst, carbonyl halide, solvent and base MITSUI TOATSU CHEMICALS, INC. (JP) 1994-10-25 US disclosed
EP-0581074-A2 Processes for producing aromatic polycarbonate oligomer and aromatic polycarbonate MITSUI TOATSU CHEMICALS, Inc. (JP) 1994-02-02 EP disclosed
EP-0575870-A1 Aromatic polycarbonate and process for production thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-12-29 EP disclosed
US-4059565-A Process for producing a branched polycarbonate or poly(ester-carbonate) MITSUBISHI GAS CHEMICAL COMPANY, INC. (JA) 1977-11-22 US disclosed