SCHEMBL890486

SCHEMBL890486

O=C(Cl)Oc1cc(C(=O)Cl)cc(C(=O)Cl)c1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.31
ALDH1A1 P00352 2/20 0.31
TSHR P16473 1/20 0.31
GLRA1 P23415 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11699992 0.95 MEN1 (0.32) ALDH1A1TSHRGLRA1
SCHEMBL11702300 0.92 TPMT (0.40) POLBALDH1A1TSHR
SCHEMBL11700120 0.87 CA12 (0.37) ALDH1A1GLRA1
SCHEMBL7753605 0.84 TPMT (0.44) POLBALDH1A1TSHR
SCHEMBL195019 0.82 LMNA (0.43) POLBALDH1A1
SCHEMBL9176348 0.82 ALDH1A1 (0.32) ALDH1A1TSHR
SCHEMBL998315 0.82 KMT2A (0.39) ALDH1A1TSHR
SCHEMBL17237455 0.81 KMT2A (0.37)
SCHEMBL5025919 0.79 TPMT (0.44) POLBALDH1A1TSHR
SCHEMBL38576 0.79 ALDH1A1 (0.40) ALDH1A1TSHRGLRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12623190-B2 Fabrication of aquaporin-based biomimetic membrane NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2026-05-12 US claimed
CN-119524650-A High-flux chlorine-resistant acid-alkali-resistant reverse osmosis composite membrane and preparation method thereof 中国矿业大学(北京) 2025-02-28 CN claimed
US-12048897-B2 Forward osmosis membrane and method of forming a forward osmosis membrane NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2024-07-30 US claimed
CN-118203957-A Solvent-resistant separation membrane resistant to pure solvent and mixed solvent system and preparation method thereof 苏州纳信膜技术有限公司 2024-06-18 CN claimed
CN-113543871-A Manufacture of aquaporin based biomimetic membranes 南洋理工大学 2021-10-22 CN claimed
EP-3568231-A1 REMOVING METAL IONS FROM AQUEOUS SYSTEMS WITH AN ACTIVE LAYER MEMBRANE BASF SE (DE) 2019-11-20 EP claimed
WO-2012102680-A1 A FORWARD OSMOSIS MEMBRANE AND METHOD OF FORMING A FORWARD OSMOSIS MEMBRANE NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2012-08-02 WO claimed
US-20110168631-A1 METHODS AND APPARATUSES FOR WATER FILTRATION USING POLYARYLETHER MEMBRANES GENERAL ELECTRIC COMPANY (US) 2011-07-14 US claimed
US-5693227-A POLYMERIZATION OF MOLECULES HAVING ELECTROPHILIC AND NUCLEOPHILIC SUBSTITUENTS ON THE SAME OR DIFFERENT MOLECULES; REGENERATION OF AMINOPYRIDINE CATALYSTS IONICS, INCORPORATED (US) 1997-12-02 US claimed
EP-0473459-B1 Reverse osmosis membranes of polyamideurethane DU PONT (US) 1995-07-26 EP claimed
EP-0621256-A1 Chloroformyloxy-substituted isophthaloyl chlorides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-10-26 EP claimed
US-5137606-A Forming chloroformyloxy-substituted isophthaloyl chloride; reacting hydroxy-substituted isophthalic acid, catlayst, phosgene, solvent E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-08-11 US claimed
EP-0473459-A2 Reverse osmosis membranes of polyamideurethane E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-03-04 EP claimed
US-5085777-A Improved solute rejection and permeation properties E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-02-04 US claimed
US-12623190-B2 Fabrication of aquaporin-based biomimetic membrane NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2026-05-12 US disclosed
CN-119524650-A High-flux chlorine-resistant acid-alkali-resistant reverse osmosis composite membrane and preparation method thereof 中国矿业大学(北京) 2025-02-28 CN disclosed
CN-118807467-B Nanofiltration membrane and preparation method thereof 湖南沁森高科新材料有限公司 2025-01-17 CN disclosed
EP-0473459-A2 Reverse osmosis membranes of polyamideurethane E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-03-04 EP disclosed
US-5085777-A Improved solute rejection and permeation properties E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-02-04 US disclosed
US-4059565-A Process for producing a branched polycarbonate or poly(ester-carbonate) MITSUBISHI GAS CHEMICAL COMPANY, INC. (JA) 1977-11-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12623190-B2 Fabrication of aquaporin-based biomimetic membrane AQP4, AQP1, AQP3 POLB 3960/4885ALDH1A1 4849/4885TSHR 3880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.