Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 12/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.34 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5026112 | 0.81 | MKNK2 (0.39) | — | |
| SCHEMBL5136443 | 0.70 | PTGS2 (0.42) | PTGS2PTGS1 | |
| SCHEMBL5084438 | 0.70 | PLAT (0.36) | PTGS2PTGS1PLAT | |
| SCHEMBL4790571 | 0.69 | KMT2A (0.45) | — | |
| SCHEMBL385101 | 0.64 | GPR183 (0.58) | PTGS2PTGS1 | |
| SCHEMBL4971991 | 0.63 | PTGS2 (0.48) | PTGS2PTGS1 | |
| SCHEMBL387949 | 0.63 | GPR119 (0.46) | PTGS2PTGS1PLAT | |
| Hydrochloric Acid SCHEMBL387557 | 0.63 | GPR183 (0.57) | PTGS2PTGS1 | |
| Hydrochloric Acid SCHEMBL15540179 | 0.63 | GPR183 (0.57) | PTGS2PTGS1 | |
| SCHEMBL5079994 | 0.62 | RORC (0.41) | PLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902028-A2 | HISTAMINE H3 RECEPTOR ANTAGONISTS | Novo Nordisk A/S (DK) | 2008-03-26 | — | — | EP | disclosed |
| WO-2007003604-A2 | HISTS1MINE H3 RECEPTOR ANTAGONISTS | NOVO NORDISK A/S (DK) | 2007-01-11 | — | — | WO | disclosed |