Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | CHUK | O15111 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4048443 | 0.83 | RORC (0.47) | PLATNOS3NOS1NOS2PTGS1 | |
| SCHEMBL3983476 | 0.83 | PLAT (0.39) | PLATSLC6A2SLC6A4SLC6A3NOS3 | |
| SCHEMBL4974300 | 0.82 | GPR119 (0.41) | KCNH2 | |
| SCHEMBL5079994 | 0.81 | RORC (0.41) | PLATSLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL14262620 | 0.77 | GPR119 (0.57) | — | |
| SCHEMBL5079948 | 0.72 | RORC (0.41) | PLATSLC6A2SLC6A4SLC6A3PTGS1 | |
| SCHEMBL17674424 | 0.70 | PTGS2 (0.41) | PTGS1PTGS2 | |
| SCHEMBL4974436 | 0.70 | PTGS2 (0.43) | PTGS1PTGS2 | |
| SCHEMBL5082147 | 0.70 | RORC (0.44) | PLATSLC6A2SLC6A4SLC6A3NOS3 | |
| SCHEMBL5026080 | 0.70 | PTGS2 (0.37) | PLATPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008025799-A1 | PYRIDAZINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS | BIOVITRUM AB (PUBL) (SE) | 2008-03-06 | — | — | WO | claimed |