Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 5/20 | 0.40 |
| ▸ | FAAH | O00519 | 4/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | CNR1 | P21554 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | OGG1 | O15527 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5017280 | 0.84 | HRH3 (0.45) | MEN1KMT2AKDM4EHSD17B10TSHR | |
| SCHEMBL1306561 | 0.78 | CNR2 (0.47) | KMT2AKDM4ETSHRCNR1ALDH1A1 | |
| SCHEMBL1306558 | 0.78 | CNR2 (0.47) | KMT2AKDM4ETSHRCNR1ALDH1A1 | |
| SCHEMBL3816745 | 0.78 | ALDH1A1 (0.55) | MEN1KMT2AKDM4EHSD17B10TSHR | |
| SCHEMBL3816749 | 0.78 | ALDH1A1 (0.55) | MEN1KMT2AKDM4EHSD17B10TSHR | |
| SCHEMBL1305961 | 0.77 | L3MBTL1 (0.48) | KMT2AKDM4EHSD17B10TSHRL3MBTL1 | |
| SCHEMBL1305962 | 0.77 | L3MBTL1 (0.48) | KMT2AKDM4EHSD17B10TSHRL3MBTL1 | |
| SCHEMBL1308527 | 0.77 | HPGD (0.49) | MEN1KMT2AKDM4ETSHRALDH1A1 | |
| SCHEMBL1308523 | 0.77 | HPGD (0.49) | MEN1KMT2AKDM4ETSHRALDH1A1 | |
| SCHEMBL22403025 | 0.76 | HTR1B (0.45) | KDM4ETSHRCNR1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945606-A1 | ALKYLCARBAMOYL NAPHTHALENYLOXY- OCTENOYLHYDROXYAMIDE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND PREPARATION THEREOF | Korea Research Institute of Chemical Technology (KR) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007052938-A1 | ALKYLCARBAMOYL NAPHTHALENYLOXY- OCTENOYLHYDROXYAMIDE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2007-05-10 | — | — | WO | disclosed |