Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.39 |
| ▸ | TUBB | P07437 | 2/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL502650 | 1.00 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4DCYP3A4 | |
| SCHEMBL503154 | 0.76 | ABCG2 (0.57) | ABCG2TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL503155 | 0.76 | ABCG2 (0.57) | ABCG2TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL3655501 | 0.72 | TUBB4A (0.48) | PDE4APDE4BPDE4CPDE4DCYP3A4 | |
| SCHEMBL5462358 | 0.69 | RECQL (0.56) | PDE4APDE4BPDE4CPDE4DCYP3A4 | |
| SCHEMBL5462360 | 0.69 | RECQL (0.56) | PDE4APDE4BPDE4CPDE4DCYP3A4 | |
| SCHEMBL28187635 | 0.69 | MAPT (0.52) | PDE4APDE4BPDE4CPDE4DCYP3A4 | |
| SCHEMBL4886498 | 0.68 | KDM4E (0.59) | MAPTHTTMEN1ALDH1A1KMT2A | |
| SCHEMBL502651 | 0.68 | TUBB1 (0.43) | PDE4APDE4BPDE4CPDE4DCYP3A4 | |
| SCHEMBL4625442 | 0.68 | TUBB1 (0.58) | CYP3A4MAPTHTTABCG2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8293898-B2 | Luminophores | UNIVERSITY OF YORK (GB) | 2012-10-23 | — | — | US | disclosed |
| US-20120157681-A1 | LUMINOPHORES | UNIVERSITY OF YORK (GB) | 2012-06-21 | — | — | US | disclosed |
| US-8106193-B2 | Luminophores | UNIVERSITY OF YORK (GB) | 2012-01-31 | — | — | US | disclosed |
| US-20100317851-A1 | LUMINOPHORES | UNIVERSITY OF YORK (GB) | 2010-12-16 | — | — | US | disclosed |
| EP-2207784-A1 | LUMINOPHORES | University of York (GB) | 2010-07-21 | — | — | EP | disclosed |
| WO-2009040551-A1 | LUMINOPHORES | UNIVERSITY OF YORK (GB) | 2009-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157681-A1 | LUMINOPHORES | PPOX, CRY1, MPO | PDE4A 4431/4885PDE4B 4735/4885PDE4C 4432/4885 |
| US-20100317851-A1 | LUMINOPHORES | PPOX, CRY1, MPO | PDE4A 4515/4885PDE4B 4733/4885PDE4C 4497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.