Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HNF4A | P41235 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29788088 | 0.87 | AKR1C2 (0.41) | FOLH1KDM4EALDH1A1SMN1; SMN2HNF4A | |
| SCHEMBL28153772 | 0.82 | HNF4A (0.54) | FOLH1KDM4EALDH1A1SMN1; SMN2HNF4A | |
| SCHEMBL5728666 | 0.79 | HNF4A (0.48) | FOLH1KDM4EALDH1A1HNF4APTPN1 | |
| SCHEMBL16911507 | 0.78 | HNF4A (0.58) | FOLH1KDM4EALDH1A1SMN1; SMN2HNF4A | |
| SCHEMBL2080480 | 0.78 | CES2 (0.41) | KDM4ESMN1; SMN2GRIA2GRIA4XDH | |
| SCHEMBL2569037 | 0.78 | ALDH1A1 (0.44) | KDM4EALDH1A1SMN1; SMN2MAPK1ATM | |
| SCHEMBL17799572 | 0.77 | HNF4A (0.56) | FOLH1KDM4EALDH1A1SMN1; SMN2HNF4A | |
| SCHEMBL16122421 | 0.76 | ALDH1A1 (0.42) | KDM4EALDH1A1SMN1; SMN2MAPK1ATM | |
| SCHEMBL2652913 | 0.75 | MAPK1 (0.46) | KDM4EALDH1A1SMN1; SMN2MAPK1ATM | |
| SCHEMBL28871241 | 0.75 | ALDH1A1 (0.43) | KDM4EALDH1A1SMN1; SMN2MAPK1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008092072-A2 | MODULATORS OF THE METABOTROPIC GLUTAMATE RECEPTOR SUBTYPE 5 AND USES THEREOF | GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2008-07-31 | — | — | WO | disclosed |