Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 4/20 | 0.47 |
| ▸ | GALR3 | O60755 | 2/20 | 0.47 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HUWE1 | Q7Z6Z7 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 2/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.45 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27741345 | 0.88 | PIK3CB (0.56) | LMNAHTTSMN1; SMN2ACHETSHR | |
| SCHEMBL5025315 | 0.84 | HUWE1 (0.49) | LMNAHTTSMN1; SMN2ACHEEGFR | |
| SCHEMBL5027000 | 0.81 | HUWE1 (0.44) | LMNAHTTSMN1; SMN2ACHEEGFR | |
| SCHEMBL5099543 | 0.77 | PDE4A (0.52) | LMNAHTTSMN1; SMN2ACHERAB9A | |
| SCHEMBL5139485 | 0.76 | SLC29A1 (0.46) | LMNAHTTEGFRTSHRMAPK1 | |
| SCHEMBL5087854 | 0.74 | AADAT (0.54) | — | |
| SCHEMBL11107310 | 0.74 | LMNA (0.55) | LMNAHTTSMN1; SMN2EGFRGALR3 | |
| SCHEMBL27741347 | 0.73 | HTT (0.42) | LMNAHTTSMN1; SMN2TSHRMAPK1 | |
| SCHEMBL5087859 | 0.73 | AURKA (0.40) | LMNAHTTSMN1; SMN2EGFRGAA | |
| SCHEMBL27925924 | 0.71 | HRH4 (0.53) | HTTACHEEGFRHRH4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101438288-A | Regulation of phosphoryl transferase activity of glutamine synthetase | CSIR CORP (ZA) | 2009-05-20 | — | — | CN | disclosed |
| EP-2008210-A1 | MODULATION OF PHOSPHORYL TRANSFERASE ACTIVITY OF GLUTAMINE SYNTHETASE | CSIR (ZA) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007105023-A1 | MODULATION OF PHOSPHORYL TRANSFERASE ACTIVITY OF GLUTAMINE SYNTHETASE | CSIR (ZA) | 2007-09-20 | — | — | WO | disclosed |