Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.35 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5028958 | 0.81 | ALDH1A1 (0.43) | — | |
| SCHEMBL5028952 | 0.78 | ALDH1A1 (0.44) | — | |
| SCHEMBL5029165 | 0.75 | MOGAT2 (0.43) | MGAT2MOGAT2 | |
| SCHEMBL6243985 | 0.74 | CNR2 (0.42) | USP30 | |
| SCHEMBL6444671 | 0.74 | CNR2 (0.44) | — | |
| SCHEMBL3920886 | 0.71 | PDE2A (0.43) | — | |
| SCHEMBL12468940 | 0.70 | MAOB (0.44) | AKR1C3USP30KDM1AMAOAMAOB | |
| SCHEMBL15864467 | 0.70 | USP30 (0.41) | AKR1C3USP30 | |
| SCHEMBL19049375 | 0.70 | MEN1 (0.46) | USP30MGAT2MOGAT2 | |
| SCHEMBL17095010 | 0.70 | CASP6 (0.45) | USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007393-A2 | THIAZOLE AND THIOPHENE ANALOGUES, AND THEIR USE IN TREATING AUTOIMMUNE DISEASES AND CANCERS | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College (US) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007118149-A2 | THIAZOLE AND THIOPHENE ANALOGUES, AND THEIR USE IN TREATING AUTOIMMUNE DISEASES AND CANCERS | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL LOLLEGE (US) | 2007-10-18 | — | — | WO | disclosed |