Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL569949 | 0.78 | GRIN2A (0.68) | MEN1KMT2ARXFP1GRIN2AGRIN2B | |
| SCHEMBL30382494 | 0.78 | GRIN2A (0.68) | MEN1KMT2ARXFP1GRIN2AGRIN2B | |
| SCHEMBL9245071 | 0.76 | GRIN2A (0.66) | MEN1KMT2ARXFP1GRIN2AGRIN2B | |
| SCHEMBL1223580 | 0.75 | KDM4E (0.50) | MEN1KMT2ARXFP1GRIN2AGRIN2B | |
| SCHEMBL569239 | 0.75 | GRIN2A (0.49) | MEN1KMT2ARXFP1GRIN2AGRIN2B | |
| SCHEMBL5029677 | 0.75 | MEN1 (0.46) | MEN1KMT2ARXFP1GRIN2AGRIN2B | |
| SCHEMBL6351094 | 0.74 | GPR35 (0.65) | MEN1KMT2ARXFP1GRIN2AGRIN2B | |
| SCHEMBL11416204 | 0.73 | ERN1 (0.56) | MEN1KMT2ARXFP1GRIN2AGRIN2B | |
| SCHEMBL570624 | 0.70 | KDM4E (0.51) | MEN1KMT2ARXFP1GRIN2AGRIN2B | |
| SCHEMBL31401779 | 0.69 | MEN1 (0.61) | MEN1KMT2ARXFP1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080032382-A1 | Methods and compositions for degradation of nitroaromatic and nitramine pollutants | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2008-02-07 | — | — | US | disclosed |
| US-7214509-B2 | Methods and compositions for degradation of nitroaromatic and nitramine pollutants | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2007-05-08 | — | — | US | disclosed |
| US-20050054030-A1 | Methods and compositions for degradation of nitroaromatic and nitramine pollutants | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2005-03-10 | — | — | US | disclosed |
| WO-2005019136-A2 | METHODS AND COMPOSITIONS FOR DEGRADATION OF NITROAROMATIC AND NITRAMINE POLLUTANTS | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2005-03-03 | — | — | WO | disclosed |