Sugi Predict

Sugi Predict / Compounds / SCHEMBL570624

SCHEMBL570624

SCHEMBL570624

Nc1c(C(=O)O)cc2cc(Br)ccc2c1Br

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.51
▸ GLA P06280 2/20 0.51
▸ RXFP1 Q9HBX9 3/20 0.50
▸ MEN1 O00255 2/20 0.50
▸ KMT2A Q03164 2/20 0.50
▸ GRIN2A Q12879 2/20 0.47
▸ GRIN2B Q13224 2/20 0.47
▸ GRIN2C Q14957 2/20 0.47
▸ GRIN2D O15399 1/20 0.47
▸ GPR35 Q9HC97 2/20 0.46
▸ GRIN1 Q05586 1/20 0.46
▸ PIM1 P11309 1/20 0.42
▸ EPRS1 P07814 1/20 0.40
▸ TBK1 Q9UHD2 1/20 0.40
▸ NPC1 O15118 1/20 0.40
▸ IDO1 P14902 1/20 0.40
▸ NCEH1 Q6PIU2 1/20 0.39
▸ POLB P06746 2/20 0.39
▸ MAPT P10636 2/20 0.39
▸ NR4A1 P22736 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30389895 0.84 KDM4E (0.49) KDM4EGLARXFP1MEN1KMT2A
SCHEMBL12528719 0.84 MEN1 (0.46) KDM4EGLARXFP1MEN1KMT2A
SCHEMBL951163 0.84 KDM4E (0.49) KDM4EGLARXFP1MEN1KMT2A
SCHEMBL1223580 0.82 KDM4E (0.50) KDM4EGLARXFP1MEN1KMT2A
SCHEMBL950007 0.81 MEN1 (0.55) KDM4EGLARXFP1MEN1KMT2A
SCHEMBL569949 0.81 GRIN2A (0.68) KDM4EGLARXFP1MEN1KMT2A
SCHEMBL30382494 0.81 GRIN2A (0.68) KDM4EGLARXFP1MEN1KMT2A
SCHEMBL9245071 0.80 GRIN2A (0.66) KDM4EGLARXFP1MEN1KMT2A
SCHEMBL569579 0.79 HSD17B10 (0.54) KDM4EGLARXFP1MEN1KMT2A
SCHEMBL29240299 0.74 MAPT (0.43) KDM4EMEN1KMT2AGRIN2AGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035399-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2026-02-05 — — US disclosed
US-12516078-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2026-01-06 — — US disclosed
US-20240251795-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR SYNGENTA CROP PROTECTION AG (CH) 2024-08-01 — — US disclosed
EP-4387449-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR Syngenta Crop Protection AG (CH) 2024-06-26 — — EP disclosed
CN-117813006-A Methods for controlling diamide-resistant pests and compounds thereof 先正达农作物保护股份公司 2024-04-02 — — CN disclosed
WO-2023021020-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR SYNGENTA CROP PROTECTION AG (CH) 2023-02-23 — — WO disclosed
US-20220213131-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-07-07 — — US disclosed
CN-114539323-A Organic electroluminescent material and device 环球展览公司 2022-05-27 — — CN disclosed
EP-2331552-B1 HEPATITIS C VIRUS INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2013-02-27 — — EP disclosed
WO-2012019106-A2 POSITIVE AND NEGATIVE MODULATORS OF NMDA RECEPTORS BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) 2012-02-09 — — WO disclosed
WO-2010036551-A1 HEPATITIS C VIRUS INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2010-04-01 — — WO disclosed
WO-2010036551-A1 HEPATITIS C VIRUS INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2010-04-01 — — WO disclosed
US-20100080770-A1 Hepatitis C Virus Inhibitors BRISTOL-MYERS SQUIBB COMPANY 2010-04-01 — — US disclosed
US-20100080770-A1 Hepatitis C Virus Inhibitors BRISTOL-MYERS SQUIBB COMPANY 2010-04-01 — — US disclosed
US-20100080770-A1 Hepatitis C Virus Inhibitors BRISTOL-MYERS SQUIBB COMPANY 2010-04-01 — — US disclosed
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-07-16 — — US disclosed
EP-1937664-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME Sumitomo Chemical Company, Limited (JP) 2008-07-02 — — EP disclosed
WO-2007043677-A9 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL CO (JP) 2007-06-07 — — WO disclosed
WO-2007043677-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-04-19 — — WO disclosed
WO-2007043677-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-04-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100080770-A1 Hepatitis C Virus Inhibitors HAVCR2, HCCS, PYGL KDM4E 3825/4885GLA 1870/4885RXFP1 4800/4885
US-20260035399-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SSB, SOD1, SOD3 KDM4E 2415/4885GLA 2233/4885RXFP1 1511/4885
US-20220213131-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, LOXL1, OCIAD2 KDM4E 3261/4885GLA 764/4885RXFP1 3200/4885
US-20240251795-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR DDT, NOS1, SLC11A2 KDM4E 2663/4885GLA 3846/4885RXFP1 800/4885
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same ACHE, DDT, CAT KDM4E 2028/4885GLA 2468/4885RXFP1 1639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.