Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2A | Q12879 | 2/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 4/20 | 0.43 |
| ▸ | AKR1C4 | P17516 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30382494 | 0.83 | GRIN2A (0.68) | GRIN2AGRIN2BGRIN2CMEN1KMT2A | |
| SCHEMBL569949 | 0.83 | GRIN2A (0.68) | GRIN2AGRIN2BGRIN2CMEN1KMT2A | |
| SCHEMBL9250480 | 0.83 | GRIN2D (0.44) | GRIN2AGRIN2BGRIN2CMEN1KMT2A | |
| SCHEMBL9245071 | 0.82 | GRIN2A (0.66) | GRIN2AGRIN2BGRIN2CMEN1KMT2A | |
| SCHEMBL1223580 | 0.81 | KDM4E (0.50) | GRIN2AGRIN2BGRIN2CMEN1KMT2A | |
| SCHEMBL6351094 | 0.79 | GPR35 (0.65) | GRIN2AGRIN2BGRIN2CMEN1KMT2A | |
| SCHEMBL569862 | 0.78 | GRIN2D (0.69) | GRIN2AGRIN2BGRIN2CGRIN2DGPR35 | |
| SCHEMBL11416204 | 0.78 | ERN1 (0.56) | GRIN2AGRIN2BGRIN2CMEN1KMT2A | |
| SCHEMBL569680 | 0.78 | POLB (0.63) | GRIN2AGRIN2BGRIN2CMEN1KMT2A | |
| SCHEMBL5029682 | 0.75 | MEN1 (0.50) | GRIN2AGRIN2BGRIN2CMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012019106-A2 | POSITIVE AND NEGATIVE MODULATORS OF NMDA RECEPTORS | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2012-02-09 | — | — | WO | disclosed |