SCHEMBL5029784

SCHEMBL5029784

CO[Si](Cl)(OC)OC1CCCCC1

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5029807 0.95 ACHE (0.30) ACHECA1CA2
SCHEMBL5031088 0.84 CA1 (0.35) ACHECA1CA2
SCHEMBL5029914 0.83
SCHEMBL5029872 0.77 ACHE (0.31) ACHECA1CA2
SCHEMBL11601772 0.77 NPC1 (0.32) ACHECA1CA2
SCHEMBL5027508 0.77 ACHE (0.31) ACHECA1CA2
SCHEMBL4554487 0.77 NPC1 (0.32) ACHECA1CA2
SCHEMBL5032364 0.77 ACHE (0.31) ACHECA1CA2
SCHEMBL5577290 0.76
SCHEMBL8006501 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101472959-A Ziegler-Natta catalyst with in situ-generated donor NOVOLEN TECH HOLDINGS CV (NL) 2009-07-01 CN disclosed
EP-1999167-A2 ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR Novolen Technology Holdings, C.V. (NL) 2008-12-10 EP disclosed
WO-2007106348-A2 ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) 2007-09-20 WO disclosed
US-20070213204-A1 Ziegler-Natta catalyst with in situ-generated donor NOVOLEN TECHNOLOGY HOLDINGS C.V. 2007-09-13 US disclosed