SCHEMBL5030587

SCHEMBL5030587

Oc1cccc(-c2cc(O)ccc2Oc2ccc(O)cc2-c2cccc(O)c2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 12/20 0.52
HSD17B2 P37059 11/20 0.52
PELI1 Q96FA3 2/20 0.51
CYP3A4 P08684 4/20 0.50
CYP2C9 P11712 3/20 0.50
ESR1 P03372 2/20 0.47
ESR2 Q92731 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2B6 P20813 1/20 0.47
CYP2C19 P33261 1/20 0.47
CA12 O43570 1/20 0.42
ALDH1A1 P00352 1/20 0.42
CA2 P00918 1/20 0.42
LMNA P02545 1/20 0.42
CA5A P35218 1/20 0.42
CA9 Q16790 1/20 0.42
HSD17B10 Q99714 1/20 0.42
CA14 Q9ULX7 1/20 0.42
CA5B Q9Y2D0 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9221165 0.85 CA12 (0.48) HSD17B1HSD17B2PELI1CYP3A4CYP2C9
SCHEMBL9219805 0.85 CA12 (0.48) HSD17B1HSD17B2PELI1CYP3A4CYP2C9
SCHEMBL17754365 0.77 PELI1 (0.61) HSD17B1HSD17B2PELI1CYP3A4CYP2C9
SCHEMBL30112758 0.76 CYP3A4 (0.52) HSD17B1HSD17B2PELI1CYP3A4CYP2C9
SCHEMBL9126489 0.76 CNR1 (0.43) CYP3A4CYP1A2ALDH1A1FYN
SCHEMBL28893935 0.76 LTA4H (0.53) PELI1ESR1ESR2ALOX5
SCHEMBL38660243 0.75 HSD17B1 (0.67) HSD17B1HSD17B2PELI1CYP3A4CYP2C9
SCHEMBL9215292 0.74 ALDH1A1 (0.44) PELI1CYP3A4ESR1ESR2CA12
SCHEMBL1851229 0.74 ALOX5 (0.71) HSD17B1HSD17B2PELI1CYP3A4CYP2C9
SCHEMBL30032619 0.74 ALOX5 (0.71) HSD17B1HSD17B2PELI1CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080262127-A1 FLAME RESISTANT RESIN COMPOSITION CHANG CHUN PLASTICS CO., LTD. (TW) 2008-10-23 US disclosed