SCHEMBL503257

SCHEMBL503257

O=C(O)CC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.65
CYP2C19 P33261 1/20 0.61
HIF1A Q16665 1/20 0.61
KIF11 P52732 8/20 0.47
CYP1A2 P05177 1/20 0.44
AKR1B1 P15121 1/20 0.42
MAPT P10636 1/20 0.41
KMT2A Q03164 1/20 0.41
GBA1 P04062 1/20 0.41
ALDH1A1 P00352 1/20 0.41
TSHR P16473 1/20 0.41
KCNN4 O15554 1/20 0.40
KEAP1 Q14145 1/20 0.39
HDAC3 O15379 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC10 Q969S8 1/20 0.39
HDAC11 Q96DB2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20546665 0.98 MIF (0.63) MIFCYP2C19HIF1AKIF11CYP1A2
SCHEMBL2291379 0.89 MIF (0.60) MIFCYP2C19HIF1AKIF11ALDH1A1
SCHEMBL370451 0.88 MIF (0.53) MIFCYP2C19HIF1AKIF11CYP1A2
SCHEMBL7887393 0.88 CYP2C19 (0.60) MIFCYP2C19HIF1AKIF11MAPT
SCHEMBL11615834 0.88 MIF (0.89) MIFCYP2C19HIF1AKIF11CYP1A2
SCHEMBL7887398 0.83 CYP2C19 (0.55) MIFCYP2C19HIF1AKIF11CYP1A2
SCHEMBL4619588 0.83 CYP2C19 (0.59) MIFCYP2C19HIF1AKIF11CYP1A2
SCHEMBL14980287 0.81 CYP2C19 (0.52) MIFCYP2C19HIF1AKIF11CYP1A2
SCHEMBL6551240 0.81 MIF (0.50) MIFCYP2C19HIF1AKIF11CYP1A2
SCHEMBL1492535 0.81 KIF11 (0.48) MIFCYP2C19HIF1AKIF11CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 229 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
CN-119039755-B Heat dissipation type carbon fiber battery rear cover and preparation method thereof 广东纵胜新材料股份有限公司 2025-04-11 CN claimed
CN-119039755-A Heat dissipation type carbon fiber battery rear cover and preparation method thereof 广东纵胜新材料股份有限公司 2024-11-29 CN claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
CN-115073391-B Novel crystal form of pramipexole triphenacetate and preparation method thereof 山东京卫制药有限公司 2023-04-07 CN claimed
CN-115073391-A Novel crystal form of pramipexole triphenacetate and preparation method thereof 山东京卫制药有限公司 2022-09-20 CN claimed
US-10072043-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2018-09-11 US claimed
CN-105860595-B A kind of graphene of hyperbranched poly triazole functionalization and preparation method thereof 华中科技大学 2017-11-14 CN claimed
CN-105860595-A Hyperbranched-polytriazole-functionalized graphene and preparation method thereof 华中科技大学 2016-08-17 CN claimed
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES Indiana University Research and Technology Corpora tion (US) 2016-06-23 US claimed
US-20060216510-A1 Can be used to form nanocomposites suitable for optical applications 3M INNOVATIVE PROPERTIES COMPANY 2006-09-28 US claimed
US-20060217478-A1 Methods of preparing polymer nanocomposite having surface modified nanoparticles 3M INNOVATIVE PROPERTIES COMPANY 2006-09-28 US claimed
US-20060216508-A1 Polymer nanocomposite having surface modified nanoparticles and methods of preparing same 3M INNOVATIVE PROPERTIES COMPANY 2006-09-28 US claimed
US-7033424-B2 Phase change inks XEROX CORPORATION (US) 2006-04-25 US claimed
US-20060021546-A1 Processes for preparing phase change inks XEROX CORPORATION 2006-02-02 US claimed
US-20060020141-A1 Metallized dye XEROX CORPORATION 2006-01-26 US claimed
US-20060016369-A1 PHASE CHANGE INKS XEROX CORPORATION 2006-01-26 US claimed
US-6946025-B2 Process for preparing tetra-amide compounds XEROX CORPORATION (US) 2005-09-20 US claimed
US-20050090690-A1 Process for preparing tetra-amide compounds XEROX CORPORATION 2005-04-28 US claimed
US-5663030-A A PHENYL OR NORBORNANE DERIVATIVE AS AN ADDITIVE TO REDUCE HEAT AND ENERGY REQUIRED TO FUSE THE TONER AND TO REDUCE JAMMING OF THE EQUIPMENT XEROX CORPORATION (US) 1997-09-02 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10072043-B2 Inhibitors of protein tyrosine phosphatases PTPRCAP, PTPRF, PTPRS MIF 3696/4885CYP2C19 3649/4885HIF1A 4875/4885
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS MIF 3696/4885CYP2C19 3649/4885HIF1A 4875/4885
US-20060020141-A1 Metallized dye CDYL, CDY1; CDY1B, CDYL2 MIF 1734/4885CYP2C19 1490/4885HIF1A 4440/4885
US-20050090690-A1 Process for preparing tetra-amide compounds TAF9, TAF5, TAF1 MIF 1696/4885CYP2C19 1364/4885HIF1A 3772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.