SCHEMBL5032698

SCHEMBL5032698

CCC(C)OP(=O)(O)CBr

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LAP3 P28838 1/20 0.33
METAP1 P53582 1/20 0.32
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP3 P08254 1/20 0.32
SMPD1 P17405 3/20 0.31
PPARD Q03181 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1039032 0.83 PPARD (0.32) LAP3METAP1MMP1MMP2MMP3
SCHEMBL776263 0.82 LAP3 (0.36) LAP3METAP1MMP1MMP2MMP3
SCHEMBL2834718 0.80 MMP1 (0.32) MMP1MMP2MMP3SMPD1PPARD
SCHEMBL1251447 0.80 PPARD (0.35) LAP3METAP1MMP1MMP2MMP3
SCHEMBL11745106 0.80 LAP3 (0.34) LAP3METAP1MMP1MMP2MMP3
SCHEMBL4623191 0.79 PLA2G2C (0.33) MMP1MMP2MMP3SMPD1
SCHEMBL4574776 0.78 LAP3 (0.33) LAP3METAP1MMP1MMP2MMP3
SCHEMBL2118428 0.78 LAP3 (0.38) LAP3METAP1MMP1MMP2MMP3
SCHEMBL10794621 0.78 LAP3 (0.33) LAP3METAP1MMP1MMP2MMP3
SCHEMBL3090613 0.78 METAP1 (0.36) LAP3METAP1SMPD1PPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118271578-A Polymer with phosphonic acid structure in side chain, synthesis method and application thereof in high-temperature proton exchange membrane fuel cell 中国科学院山西煤炭化学研究所 2024-07-02 CN claimed
EP-3801553-B1 PRODRUGS OF FULVESTRANT KASHIV BIOSCIENCES LLC (US) 2026-03-25 EP disclosed
US-20210253626-A1 PRODRUGS OF FULVESTRANT KI PHARMACEUTICALS, LLC 2021-08-19 US disclosed
EP-3801553-A2 PRODRUGS OF FULVESTRANT Kashiv Biosciences, LLC (US) 2021-04-14 EP disclosed
US-7462608-B2 Non nucleoside reverse transcriptase inhibitors GILEAD SCIENCES, INC. (US) 2008-12-09 US disclosed
US-20070190523-A1 Method and compositions for identifying anti-hiv therapeutic compounds GILEAD SCIENCES, INC. 2007-08-16 US disclosed
EP-1575486-A4 METHOD AND COMPOSITIONS FOR IDENTIFYING ANTI-HIV THERAPEUTIC COMPOUNDS GILEAD SCIENCES INC (US) 2007-02-28 EP disclosed
EP-1711617-A1 METHOD AND COMPOSITIONS FOR IDENTIFYING ANTI-HIV THERAPEUTICS COMPOUNDS GILEAD SCIENCES, INC. (US) 2006-10-18 EP disclosed
WO-2005064008-A9 METHOD AND COMPOSITIONS FOR IDENTIFYING ANTI-HIV THERAPEUTIC COMPOUNDS GILEAD SCIENCES INC (US) 2006-09-28 WO disclosed
US-20060128692-A1 Non nucleoside reverse transcriptase inhibitors GILEAD SCIENCES, INC (US) 2006-06-15 US disclosed
US-20050239054-A1 Method and compositions for identifying anti-HIV therapeutic compounds GILEAD SCIENCES. INC. 2005-10-27 US disclosed
EP-1575486-A2 METHOD AND COMPOSITIONS FOR IDENTIFYING ANTI-HIV THERAPEUTIC COMPOUNDS GILEAD SCIENCES, INC. (US) 2005-09-21 EP disclosed
US-20050197320-A1 Non nucleoside reverse transcriptase inhibitors GILEAD SCIENCES, INC. 2005-09-08 US disclosed
WO-2005064008-A1 METHOD AND COMPOSITIONS FOR IDENTIFYING ANTI-HIV THERAPEUTIC COMPOUNDS GILEAD SCIENCES, INC. (US) 2005-07-14 WO disclosed
EP-1501841-A2 NON NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS GILEAD SCIENCES, INC. (US) 2005-02-02 EP disclosed
WO-2004096818-A2 METHOD AND COMPOSITIONS FOR IDENTIFYING ANTI-HIV THERAPEUTIC COMPOUNDS GILEAD SCIENCES, INC. (US) 2004-11-11 WO disclosed
US-20040121316-A1 Method and compositions for identifying anti-HIV therapeutic compounds GILEAD SCIENCES, INC. 2004-06-24 US disclosed
WO-2003090691-A2 METHOD AND COMPOSITIONS FOR IDENTIFYING ANTI-HIV THERAPEUTIC COMPOUNDS GILEAD SCIENCES, INC. (US) 2003-11-06 WO disclosed
WO-2003091264-A2 NON NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS GILEAD SCIENCES, INC. (US) 2003-11-06 WO disclosed
US-6534489-B1 Organophosphorus compounds and the use thereof JOMAA PHARMAKA GMBH (DE) 2003-03-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060128692-A1 Non nucleoside reverse transcriptase inhibitors TYMP, PNP, ITPA LAP3 769/4885METAP1 443/4885MMP1 545/4885
US-20040121316-A1 Method and compositions for identifying anti-HIV therapeutic compounds CES1, PNP, PGLS LAP3 737/4885METAP1 964/4885MMP1 3502/4885
US-20050239054-A1 Method and compositions for identifying anti-HIV therapeutic compounds CES1, PNP, PGLS LAP3 737/4885METAP1 964/4885MMP1 3502/4885
US-20210253626-A1 PRODRUGS OF FULVESTRANT CYP19A1, PGR, CYP21A2 LAP3 1194/4885METAP1 2291/4885MMP1 4121/4885
US-20050197320-A1 Non nucleoside reverse transcriptase inhibitors TYMP, PNP, ITPA LAP3 769/4885METAP1 443/4885MMP1 545/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.