SCHEMBL5032808

SCHEMBL5032808

C=CCCCCCCCC(=O)OCCN1CCN=C1CCCCCCCC=C

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
LMNA P02545 1/20 0.40
ABCC4 O15439 1/20 0.34
MAPT P10636 1/20 0.34
DGKA P23743 1/20 0.33
FAAH O00519 2/20 0.33
TSHR P16473 1/20 0.33
MGLL Q99685 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18531247 0.95 DGKA (0.44) ALDH1A1LMNAMAPTDGKATSHR
SCHEMBL5032814 0.85 ALDH1A1 (0.46) ALDH1A1LMNAMAPTDGKATSHR
SCHEMBL5032155 0.85 DGKA (0.46) ALDH1A1MAPTDGKAFAAHMGLL
SCHEMBL9130794 0.85 DGKA (0.46) ALDH1A1MAPTDGKAFAAHMGLL
SCHEMBL9695229 0.84 DGKA (0.53) ALDH1A1LMNAMAPTDGKATSHR
SCHEMBL9190465 0.84 DGKA (0.53) ALDH1A1LMNAMAPTDGKATSHR
SCHEMBL9550459 0.84 DGKA (0.53) ALDH1A1LMNAMAPTDGKATSHR
SCHEMBL9131696 0.84 DGKA (0.53) ALDH1A1LMNAMAPTDGKATSHR
SCHEMBL9130118 0.84 DGKA (0.53) ALDH1A1LMNAMAPTDGKATSHR
SCHEMBL9132505 0.84 DGKA (0.53) ALDH1A1LMNAMAPTDGKATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10322994-B2 Fatty amides and derivatives from natural oil metathesis STEPAN COMPANY (US) 2019-06-18 US disclosed
US-9688944-B2 Synergistic surfactant blends STEPAN COMPANY (US) 2017-06-27 US disclosed
US-20170158617-A1 FATTY AMIDES AND DERIVATIVES FROM NATURAL OIL METATHESIS STEPAN CO (US) 2017-06-08 US disclosed
US-20170158617-A1 FATTY AMIDES AND DERIVATIVES FROM NATURAL OIL METATHESIS STEPAN CO (US) 2017-06-08 US disclosed
US-9573884-B2 Imidazoline amides and derivitives from natural oil metathesis STEPAN COMPANY (US) 2017-02-21 US disclosed
US-9573884-B2 Imidazoline amides and derivitives from natural oil metathesis STEPAN COMPANY (US) 2017-02-21 US disclosed
EP-2632256-B1 FATTY AMIDES AND DERIVATIVES FROM NATURAL OIL METATHESIS STEPAN CO (US) 2017-02-01 EP disclosed
US-9249374-B2 Light-duty liquid detergents based on compositions derived from natural oil metathesis STEPAN COMPANY (US) 2016-02-02 US disclosed
US-9249374-B2 Light-duty liquid detergents based on compositions derived from natural oil metathesis STEPAN COMPANY (US) 2016-02-02 US disclosed
US-20150376118-A1 FATTY AMIDES AND DERIVATIVES FROM NATURAL OIL METATHESIS STEPAN CO (US) 2015-12-31 US disclosed
US-20150376118-A1 FATTY AMIDES AND DERIVATIVES FROM NATURAL OIL METATHESIS STEPAN CO (US) 2015-12-31 US disclosed
US-9175245-B2 Fatty amides and derivatives from natural oil metathesis STEPAN COMPANY (US) 2015-11-03 US disclosed
US-9175245-B2 Fatty amides and derivatives from natural oil metathesis STEPAN COMPANY (US) 2015-11-03 US disclosed
US-20130288946-A1 LIGHT-DUTY LIQUID DETERGENTS BASED ON COMPOSITIONS DERIVED FROM NATURAL OIL METATHESIS STEPAN COMPANY (US) 2013-10-31 US disclosed
US-20130288946-A1 LIGHT-DUTY LIQUID DETERGENTS BASED ON COMPOSITIONS DERIVED FROM NATURAL OIL METATHESIS STEPAN COMPANY (US) 2013-10-31 US disclosed
US-20130225470-A1 FATTY AMIDES AND DERIVATIVES FROM NATURAL OIL METATHESIS STEPAN COMPANY (US) 2013-08-29 US disclosed
US-20130225470-A1 FATTY AMIDES AND DERIVATIVES FROM NATURAL OIL METATHESIS STEPAN COMPANY (US) 2013-08-29 US disclosed
WO-2012061110-A1 LIGHT-DUTY LIQUID DETERGENTS BASED ON COMPOSITIONS DERIVED FROM NATURAL OIL METATHESIS STEPAN COMPANY (US) 2012-05-10 WO disclosed
WO-2012061094-A1 FATTY AMIDES AND DERIVATIVES FROM NATURAL OIL METATHESIS STEPAN COMPANY (US) 2012-05-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130225470-A1 FATTY AMIDES AND DERIVATIVES FROM NATURAL OIL METATHESIS SGMS1, DEGS1, DGAT2 ALDH1A1 671/4885LMNA 3734/4885ABCC4 3404/4885
US-20170158617-A1 FATTY AMIDES AND DERIVATIVES FROM NATURAL OIL METATHESIS DEGS1, SGMS1, DGAT2 ALDH1A1 656/4885LMNA 3964/4885ABCC4 3353/4885
US-20150376118-A1 FATTY AMIDES AND DERIVATIVES FROM NATURAL OIL METATHESIS DEGS1, SGMS1, DGAT2 ALDH1A1 656/4885LMNA 3964/4885ABCC4 3353/4885
US-10322994-B2 Fatty amides and derivatives from natural oil metathesis DEGS1, SGMS1, DGAT2 ALDH1A1 656/4885LMNA 3964/4885ABCC4 3353/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.