Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.70 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.70 |
| ▸ | SHBG | P04278 | 1/20 | 0.70 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.69 |
| ▸ | MAOB | P27338 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | GAPDH | P04406 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | TNKS | O95271 | 1/20 | 0.60 |
| ▸ | BCHE | P06276 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | ACHE | P22303 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4796576 | 0.98 | ESR1 (0.68) | ESR1ESR2SHBGALOX5MAOB | |
| SCHEMBL4659168 | 0.88 | MAOB (0.78) | ESR1ESR2SHBGALOX5MAOB | |
| SCHEMBL5432580 | 0.86 | ALOX5 (0.66) | ESR1ESR2SHBGALOX5MAOB | |
| Stemofuran A SCHEMBL29742935 | 0.85 | TYR (0.68) | ESR1ESR2SHBGALOX5MAOB | |
| Stemofuran A SCHEMBL28792809 | 0.85 | TYR (0.68) | ESR1ESR2SHBGALOX5MAOB | |
| SCHEMBL5768216 | 0.84 | MAOB (0.72) | ALOX5MAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL731363 | 0.84 | MAOB (0.71) | ALOX5MAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31105656 | 0.84 | MAOB (0.71) | ALOX5MAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29941531 | 0.82 | ESR1 (1.00) | ESR1ESR2SHBGMAOBNPC1 | |
| SCHEMBL9138143 | 0.82 | SHBG (1.00) | ESR1ESR2SHBGALOX5MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11384060-B2 | Amide compounds and use thereof | ALPHALA CO., LTD. (TW) | 2022-07-12 | — | — | US | disclosed |
| US-11384060-B2 | Amide compounds and use thereof | ALPHALA CO., LTD. (TW) | 2022-07-12 | — | — | US | disclosed |
| US-20200255572-A1 | THERMOPLASTIC POLYMERS SYNTHESIZED FROM DEPOLYMERIZED LIGNIN VIA FREE RADICAL POLYMERIZATION | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2020-08-13 | — | — | US | disclosed |
| US-20190337915-A1 | AMIDE COMPOUNDS AND USE THEREOF | ALPHALA CO., LTD. (TW) | 2019-11-07 | — | — | US | disclosed |
| US-20190337915-A1 | AMIDE COMPOUNDS AND USE THEREOF | ALPHALA CO., LTD. (TW) | 2019-11-07 | — | — | US | disclosed |
| WO-2018140339-A1 | AMIDE COMPOUNDS AND USE THEREOF | ALPHALA CO., LTD. (TW) | 2018-08-02 | — | — | WO | disclosed |
| CN-107698571-A | Naphthalimide-coumarin DNA targeting double-intercalator, synthesis and application thereof | 大连理工大学 | 2018-02-16 | — | — | CN | disclosed |
| WO-2017204554-A2 | METHOD FOR PREPARING SILANE DERIVATIVES FROM FURAN DERIVATIVES IN PRESENCE OF BORANE CATALYST | 기초과학연구원 | 2017-11-30 | — | — | WO | disclosed |
| US-20110212940-A1 | S1P Receptor Modulating Compounds and Use Thereof | EPIX PHARMACEUTICALS, INC. (US) | 2011-09-01 | — | — | US | disclosed |
| US-7919519-B2 | 1-(4-(5-Phenylbenzofuran-2-yl)benzyl)azetidine-3-carboxylic acids; anticarcinogenic, antiinflammatory, antiarthritic, antidiabetic agents; transplant rejection, autoimmune diseases, lupus, multiple sclerosis, psoriasis, inflammatory bowel disease, Chron's disease | EPIX PHARMACEUTICALS INC. (US) | 2011-04-05 | — | — | US | disclosed |
| US-20080027036-A1 | S1P receptor modulating compounds and use thereof | EPIX DELAWARE, INC. (US) | 2008-01-31 | — | — | US | disclosed |
| US-20070173487-A1 | S1P receptor modulating compounds and use thereof | PREDIX PHARMACEUTICAL HOLDINGS | 2007-07-26 | — | — | US | disclosed |
| EP-1689732-A2 | CATIONIC SUBSTITUTED BENZOFURANS AS ANTIMICROBIAL AGENTS | The University of North Carolina at Chapel Hill (US) | 2006-08-16 | — | — | EP | disclosed |
| US-20050197378-A1 | Cationic substituted benzofurans as antimicrobial agents | TIDWELL RICHARD R (US) | 2005-09-08 | — | — | US | disclosed |
| WO-2005055935-A2 | CATIONIC SUBSTITUTED BENZOFURANS AS ANTIMICROBIAL AGENTS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2005-06-23 | — | — | WO | disclosed |
| US-4766223-A | FROM ALKYL BENZOFURAN AND 4-METHOXYBENZOYL HALIDE; HYDROLYSIS, DEMETHYLATION | SANOFI (FR) | 1988-08-23 | — | — | US | disclosed |
| US-4187234-A | FIRBRINOLYTIC AND THROMBOLYTIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1980-02-05 | — | — | US | disclosed |
| US-4001426-A | HAVING CORONARY VASODILATOR ACTIVITY | SMITHKLINE CORPORATION (US) | 1977-01-04 | — | — | US | disclosed |
| US-3810990-A | INHIBITING GROWTH OF BACTERIA | US AGRICULTURE | 1974-05-14 | — | — | US | disclosed |
| US-3745218-A | PRESERVATION PROCESS USING 2-(4-HYDROXYPHENYL)-BENZOFURAN | US AGRICULTURE | 1973-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027036-A1 | S1P receptor modulating compounds and use thereof | S1PR1, S1PR5, S1PR2 | ESR1 2497/4885ESR2 1688/4885SHBG 698/4885 |
| US-20190337915-A1 | AMIDE COMPOUNDS AND USE THEREOF | GLP1R, IAPP, GPR119 | ESR1 1404/4885ESR2 1515/4885SHBG 376/4885 |
| US-20110212940-A1 | S1P Receptor Modulating Compounds and Use Thereof | S1PR1, S1PR5, S1PR2 | ESR1 2497/4885ESR2 1688/4885SHBG 698/4885 |
| US-20050197378-A1 | Cationic substituted benzofurans as antimicrobial agents | BET1, ARG2, BRDT | ESR1 4263/4885ESR2 4292/4885SHBG 4552/4885 |
| US-20070173487-A1 | S1P receptor modulating compounds and use thereof | S1PR1, S1PR5, S1PR2 | ESR1 2497/4885ESR2 1688/4885SHBG 698/4885 |
| US-11384060-B2 | Amide compounds and use thereof | GLP1R, IAPP, GPR119 | ESR1 1404/4885ESR2 1515/4885SHBG 376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.