Phenylalanine

Phenylalanine

SCHEMBL503311

C.N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 4/20 0.96
PTGS1 P23219 2/20 0.96
ALPI P09923 1/20 0.96
PKM P14618 1/20 0.96
XIAP P98170 1/20 0.96
SLC1A3 P43003 2/20 0.67
SLC1A2 P43004 2/20 0.67
SLC1A1 P43005 2/20 0.67
SLC15A1 P46059 1/20 0.61
CYP1A2 P05177 1/20 0.59
LTA4H P09960 1/20 0.58
GRIA2 P42262 1/20 0.57
KDM4E B2RXH2 1/20 0.56
USP2 O75604 1/20 0.56
EGFR P00533 1/20 0.56
LCK P06239 1/20 0.56
FYN P06241 1/20 0.56
ADORA3 P0DMS8 1/20 0.56
ALOX15 P16050 1/20 0.56
HTR2A P28223 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dl-Phenylalanine SCHEMBL11103233 1.00 SLC7A5 (0.96) SLC7A5PTGS1ALPIPKMXIAP
D-Phenylalanine SCHEMBL503309 1.00 SLC7A5 (0.96) SLC7A5PTGS1ALPIPKMXIAP
Dl-Phenylalanine SCHEMBL1449124 0.98 SLC7A5 (1.00) SLC7A5PTGS1ALPIPKMXIAP
Dl-Phenylalanine SCHEMBL8118 0.98 SLC7A5 (1.00) SLC7A5PTGS1ALPIPKMXIAP
Dl-Phenylalanine SCHEMBL15671104 0.98 SLC7A5 (1.00) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL23159186 0.98 SLC7A5 (1.00) SLC7A5PTGS1ALPIPKMXIAP
Dl-Phenylalanine SCHEMBL1331985 0.98 SLC7A5 (1.00) SLC7A5PTGS1ALPIPKMXIAP
Phenylalanine SCHEMBL16398197 0.98 SLC7A5 (1.00) SLC7A5PTGS1ALPIPKMXIAP
D-Phenylalanine SCHEMBL837632 0.98 SLC7A5 (1.00) SLC7A5PTGS1ALPIPKMXIAP
Dl-Phenylalanine SCHEMBL385804 0.98 SLC7A5 (1.00) SLC7A5PTGS1ALPIPKMXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 401 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4680629-A1 STAPLED PEPTIDES The Florey Institute Of Neuroscience And Mental Health (AU) 2026-01-21 EP claimed
WO-2024187241-A1 STAPLED PEPTIDES THE FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH (AU) 2024-09-19 WO claimed
US-11976137-B2 Compounds for use as apelin receptor antagonists CAMBRIDGE ENTERPRISE LIMITED (GB) 2024-05-07 US claimed
US-11566057-B2 Long-acting co-agonists of the glucagon and GLP-1 receptors MERCK SHARP & DOHME LLC (US) 2023-01-31 US claimed
US-11492385-B2 Long-acting co-agonists of the glucagon and GLP-1 receptors MERCK SHARP & DOHME LLC (US) 2022-11-08 US claimed
US-20210155659-A1 COMPOUNDS FOR USE AS APELIN RECEPTOR ANTAGONISTS CAMBRIDGE ENTERPRISE LIMITED (GB) 2021-05-27 US claimed
EP-3773663-A1 COMPOUNDS FOR USE AS APELIN RECEPTOR ANTAGONISTS Cambridge Enterprise Limited (GB) 2021-02-17 EP claimed
US-20200392196-A1 LONG-ACTING CO-AGONISTS OF THE GLUCAGON AND GLP-1 RECEPTORS MERCK SHARP & DOHME CORP. (US) 2020-12-17 US claimed
US-10793615-B2 Long-acting co-agonists of the glucagon and GLP-1 receptors MERCK SHARP & DOHME CORP. (US) 2020-10-06 US claimed
EP-3700550-A1 LONG-ACTING CO-AGONISTS OF THE GLUCAGON AND GLP-1 RECEPTORS Merck Sharp & Dohme Corp. (US) 2020-09-02 EP claimed
US-20200270325-A1 LONG-ACTING CO-AGONISTS OF THE GLUCAGON AND GLP-1 RECEPTORS MERCK SHARP & DOHME CORP. (US) 2020-08-27 US claimed
CN-111132690-A Long-acting co-agonists of glucagon and GLP-1 receptor 默沙东公司 2020-05-08 CN claimed
US-20190338008-A1 LONG-ACTING CO-AGONISTS OF THE GLUCAGON AND GLP-1 RECEPTORS MERCK SHARP & DOHME LLC 2019-11-07 US claimed
WO-2019193355-A1 COMPOUNDS FOR USE AS APELIN RECEPTOR ANTAGONISTS DAVENPORT ANTHONY PETER (GB) 2019-10-10 WO claimed
WO-2019060660-A1 LONG-ACTING CO-AGONISTS OF THE GLUCAGON AND GLP-1 RECEPTORS MERCK SHARP & DOHME CORP. (US) 2019-03-28 WO claimed
EP-3377521-A2 LONG-ACTING CO-AGONISTS OF THE GLUCAGON AND GLP-1 RECEPTORS Merck Sharp & Dohme Corp. (US) 2018-09-26 EP claimed
WO-2017074798-A2 LONG-ACTING CO-AGONISTS OF THE GLUCAGON AND GLP-1 RECEPTORS MERCK SHARP & DOHME CORP. (US) 2017-05-04 WO claimed
US-20260116921-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES PROTAGONIST THERAPEUTICS INC (US) 2026-04-30 US disclosed
US-4435571-A 5-(Substituted benzyl)-6-oxo-2-piperazine carboxylic acids and esters RICHARDSON MERRELL INC. (US) 1984-03-06 US disclosed
US-4341698-A Enkaphalin derivatives RICHARDSON-MERRELL INC. (US) 1982-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11492385-B2 Long-acting co-agonists of the glucagon and GLP-1 receptors GLP1R, GCGR, GIPR SLC7A5 3291/4885PTGS1 1221/4885ALPI 1169/4885
US-11976137-B2 Compounds for use as apelin receptor antagonists APLNR, GIPR, GRPR SLC7A5 2343/4885PTGS1 1137/4885ALPI 1061/4885
US-11566057-B2 Long-acting co-agonists of the glucagon and GLP-1 receptors GLP1R, GCGR, GIPR SLC7A5 3291/4885PTGS1 1221/4885ALPI 1169/4885
US-20210155659-A1 COMPOUNDS FOR USE AS APELIN RECEPTOR ANTAGONISTS APLNR, GIPR, GRPR SLC7A5 2343/4885PTGS1 1137/4885ALPI 1061/4885
US-20200270325-A1 LONG-ACTING CO-AGONISTS OF THE GLUCAGON AND GLP-1 RECEPTORS GLP1R, GCGR, GIPR SLC7A5 3291/4885PTGS1 1221/4885ALPI 1169/4885
US-20260116921-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES IL23R, IL1RN, IL36G SLC7A5 1439/4885PTGS1 1487/4885ALPI 1053/4885
US-10793615-B2 Long-acting co-agonists of the glucagon and GLP-1 receptors GLP1R, GCGR, GIPR SLC7A5 3291/4885PTGS1 1221/4885ALPI 1169/4885
US-20200392196-A1 LONG-ACTING CO-AGONISTS OF THE GLUCAGON AND GLP-1 RECEPTORS GLP1R, GCGR, GIPR SLC7A5 3291/4885PTGS1 1221/4885ALPI 1169/4885
US-20190338008-A1 LONG-ACTING CO-AGONISTS OF THE GLUCAGON AND GLP-1 RECEPTORS GLP1R, GCGR, GIPR SLC7A5 3291/4885PTGS1 1221/4885ALPI 1169/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.